Oncology & Cancer

RNA stability may play a role in prostate cancer

Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from scientists at Fred Hutchinson Cancer Center published in Cell Reports.

Genetics

Scientists spot 32 proteins that hint at Alzheimer's risk

It's difficult to fully predict who will develop Alzheimer's disease in advance. Now, a new study suggests that certain markers in the blood may occur 10 to 20 years before the start of symptoms and could help doctors determine ...

Medical research

Researchers solve structure of immune-evading HIV protein complex

The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...

Oncology & Cancer

Researchers target mutation that leads to pancreatic cancer

After 30 years of discouraging results in attempting to develop drugs to inhibit a mutated protein associated with some of the more challenging cancers to treat, research on RAS proteins is booming.

Oncology & Cancer

A two-for-one approach to boost melanoma immunotherapy

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...

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