Medical research

Breakthrough brings potential glioblastoma drug into focus

Glioblastoma, the most common cancerous brain tumor in adults, is an aggressive disease—patients survive an average of just 15 months once they are diagnosed. Despite more than two decades of research on the causes and ...

Neuroscience

Toxic protein 'variant' may be the next target for ALS therapies

Scientists have long known that proteins can form harmful clusters in neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). But a new study by Penn State researchers ...

Oncology & Cancer

How pancreatic cancer cells dodge drug treatments

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory (CSHL) Cancer Center Director David Tuveson and his team investigated ...

Alzheimer's disease & dementia

A new model of Alzheimer's progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease ...

Genetics

Reactivating aging stem cells in the brain

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers at the University of Zurich have now discovered a mechanism linked ...

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