News tagged with protein family
Gene discoveries give hope against 'Brittle bone' disease
(HealthDay)—Mutations in a gene involved in bone development appear to cause certain severe forms of bone loss, a finding that could lead to new therapies for the common bone-thinning disorder osteoporosis, ...
Genetics
May 08, 2013 |
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Research team uncovers shape of transmembrane protein partly responsible for antibiotic resistance
(Medical Xpress)—Researchers from the University of Tokyo have uncovered the physical layout of a transmembrane protein that the tiny organism Archaea relies on to keep toxins out of its cells. The protein, ...
Medical research
Mar 28, 2013 |
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Team finds general mechanism that accelerates tumor development
ICREA professor Raúl Méndez publishes a study in Nature describing how the CPBE1 protein "takes the brakes off" the production of proteins associated with the cell switch from being healthy to tumorous. ...
Cancer
Feb 24, 2013 |
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Immune cell death defects linked to autoimmune diseases
Melbourne researchers have discovered that the death of immune system cells is an important safeguard against the development of diseases such as type 1 diabetes, rheumatoid arthritis and lupus, which occur ...
Immunology
Jan 23, 2013 |
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Cancer gene family member functions key to cell adhesion and migration
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While ...
Cancer
Aug 30, 2012 |
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Scientists gain new insights into Taspase1 function
Scientists at the University Medical Center of Johannes Gutenberg University Mainz in Germany identified a novel strategy to target the oncologically relevant protein-cleaving enzyme Taspase1. Taspase1 levels are not only ...
Cancer
Jul 10, 2012 |
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Marked for destruction: Newly developed compound triggers cancer cell death
The BCL-2 protein family plays a large role in determining whether cancer cells survive in response to therapy or undergo a form of cell death known as apoptosis. Cells are pressured toward apoptosis by expression of pro-apoptotic ...
Cancer
May 24, 2012 |
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Biomarker family found for chemo resistant breast cancers
Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK.
Cancer
Apr 12, 2012 |
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Fewer mitochondria in offspring of parents with diabetes
(HealthDay) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study ...
Diabetes
Mar 26, 2012 |
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Same genes linked to early- and late-onset Alzheimer's disease
The same gene mutations linked to inherited, early-onset Alzheimer's disease have been found in people with the more common late-onset form of the illness.
Alzheimer's disease & dementia
Feb 01, 2012 |
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Small molecule hobbles dengue in vitro and in vivo
A novel compound inhibits dengue virus, as well as other closely related important human pathogens. The research is published in the September 2011 issue of the journal Antimicrobial Agents and Chemotherapy.
Diseases, Conditions, Syndromes
Sep 19, 2011 |
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In next-gen DNA sequence, new answers to a rare and devastating disease
In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of 3. The problem is that the mitochondria responsible for powering ...
Medical research
Sep 06, 2011 |
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Study: Low-income families' diets often fall short in nutrition
(Medical Xpress) -- More than seven in 10 low-income families in a new University of Nebraska-Lincoln study struggled to reach adequate levels of nutrition in their diet, researchers said.
Health
Jun 22, 2011 |
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