Health

Preventing kidney stones before they form

Kidney stones are small, hard deposits made of minerals and reoccurring materials inside the kidneys. Stones often go unnoticed in the kidney until they move into the ureter —the tube connecting the kidney and bladder.

Cardiology

Investigating the role of DNA damage in cardiac hypertrophy

A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes, which contributes to the development of cardiac hypertrophy, according to a Northwestern Medicine study published in Circulation.

Medical research

Hunt for the protein TGM1 led to disease discovery

By searching for the protein TGM1 among patients with various autoimmune skin diseases, researchers have successfully identified a separate disease that can be linked to autoimmunity against TGM1. This backward method demonstrates ...

Genetics

When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...

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