News tagged with protein fragments
Drug reverses Alzheimer's disease deficits in mice, research confirms
An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health researchers confirm in the journal Science.
Alzheimer's disease & dementia
May 23, 2013 |
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Anti-CD47 antibody may offer new route to successful cancer vaccination
(Medical Xpress)—Scientists at the School of Medicine have shown that their previously identified therapeutic approach to fight cancer via immune cells called macrophages also prompts the disease-fighting killer T cells ...
Cancer
May 21, 2013 |
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New findings on the brain's immune cells during Alzheimer's disease progression
The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But ...
Alzheimer's disease & dementia
Apr 11, 2013 |
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Study offers new way to discover HIV vaccine targets
Decades of research and three large-scale clinical trials have so far failed to yield an effective HIV vaccine, in large part because the virus evolves so rapidly that it can evade any vaccine-induced immune response.
HIV & AIDS
Mar 21, 2013 |
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Cell metabolism: Muscle loss can be caused by mitochondrial degradation induced by protein Mul1
Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide ...
Medical research
Mar 13, 2013 |
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Study shows antibody therapy clears Alzheimer's plaques in mice
Antibodies against amyloid beta (Aβ) protein deposits that are thought to play a role in Alzheimer's disease have shown some success in preventing the buildup of deposits in animals, but they have not been effective at removing ...
Alzheimer's disease & dementia
Dec 05, 2012 |
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A molecular scissor related to Alzheimer's disease
An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta). ...
Alzheimer's disease & dementia
Oct 04, 2012 |
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Researchers identify new enzyme to fight Alzheimer's disease
An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...
Alzheimer's disease & dementia
Sep 17, 2012 |
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Early activation of immune response could lead to better vaccines
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a new "first response" mechanism that the immune system uses to respond to infection. The findings challenge the current understanding ...
Immunology
Aug 30, 2012 |
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Small molecule may play big role in Alzheimer's disease
Alzheimer's disease is one of the most dreaded and debilitating illnesses one can develop. Currently, the disease afflicts 6.5 million Americans and the Alzheimer's Association projects it to increase to between ...
Alzheimer's disease & dementia
Jul 09, 2012 |
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Cholesterol drug shows benefit in animal study of Alzheimer's disease
A cholesterol drug commonly prescribed to reduce cardiovascular disease risk restores blood vessel function in a mouse model of Alzheimer's disease, according to a study in the April 4 issue of The Journal of Neuroscience. The dr ...
Alzheimer's disease & dementia
Apr 03, 2012 |
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Stem cell therapy reverses diabetes
Type 1 diabetes is caused by the body's own immune system attacking its pancreatic islet beta cells and requires daily injections of insulin to regulate the patient's blood glucose levels. A new method described in BioMed ...
Medical research
Jan 10, 2012 |
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Autism may be linked to abnormal immune system characteristics and novel protein fragment
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry ...
Immunology
Jan 03, 2012 |
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CSF test can pick up Alzheimer's early
Analysis of the cerebrospinal fluid can detect whether a person has Alzheimer's disease before symptoms appear. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have studied biomarkers that ...
Diseases, Conditions, Syndromes
Dec 20, 2011 |
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Scientists identify human proteins that may fuel HIV/AIDS transmission
Scientists at the Gladstone Institutes have discovered new protein fragments in semen that enhance the ability of HIV, the virus that causes AIDS, to infect new cells -- a discovery that one day could help ...
HIV & AIDS
Dec 14, 2011 |
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