There are two important categories of genes involved in cancer development, oncogenes and tumor suppressor genes. When oncogenes gain function, e.g. through mutation, they actively promote cancer - drugs that turn them off ...
Oct 10, 2017
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Common wisdom maintains that, because of the myriad effects on the brain, how anesthetic drugs work at the molecular level is a mystery.
Sep 11, 2017
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Rare mutations in the amyloid precursor protein (APP) have previously been shown to be strongly associated with Alzheimer's disease (AD). Common genetic variants in this protein may also be linked to intelligence (IQ) in ...
Aug 2, 2017
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A new study finds that moderate exercise does not impair kidney function in some people with chronic kidney disease (CKD). The study—the first to analyze the effects of exercise on kidney disease that does not require dialysis—is ...
Jul 13, 2017
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A study published online in The FASEB Journal demonstrated that a protein complex (Gbeta5-RGS) commonly known for halting cellular functions may actually stimulate insulin secretion in pancreatic cells. This discovery offers ...
Jul 10, 2017
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Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure. The study, "Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction," which ...
May 26, 2017
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A common complication of type 2 diabetes occurs when filters within the kidney are damaged, leading to an abnormal buildup of protein in urine and a decline in kidney function. This condition, called diabetic kidney disease, ...
May 8, 2017
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Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain. Their findings may help understand the processes ...
May 3, 2017
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A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys ...
May 3, 2017
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Fresh discoveries about a range of neurological disorders may inform the development of new therapies.
Mar 27, 2017
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