News tagged with protein kinase

Related topics: protein

How neurons get wired

Two different versions of the same signaling protein tell a nerve cell which end is which, UA researchers have discovered. The findings could help improve therapies for spinal injuries and neurodegenerative ...

Aug 14, 2013
popularity 5 / 5 (10) | comments 0 | with audio podcast

Researchers investigate 59 tumor cell lines

In what is the biggest study of its kind to date, researchers from Technische Universität München (TUM) have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted ...

Aug 08, 2013
popularity 5 / 5 (4) | comments 0

New drug may protect the heart during ischemia

Research from three Yale laboratories—in the fields of immunobiology, chemistry, and cardiology—could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out in human trials, ...

Jul 24, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Alternative target for breast cancer drugs

Scientists have identified higher levels of a receptor protein found on the surface of human breast tumour cells that may serve as a new drug target for the treatment of breast cancer. The results, which are published today ...

Jul 19, 2013
popularity not rated yet | comments 0

Mutation linked to congenital urinary tract defects

Researchers at Columbia University Medical Center (CUMC) and collaborators have identified a genetic mutation that causes congenital malformations of the kidney and urinary tract, a common form of birth defect and the most ...

Jul 17, 2013
popularity not rated yet | comments 0 | with audio podcast

Researchers find two new methods to determine ALK status

The implementation of personalized health care in cancer relies on the identification and characterization of cancer biomarkers and the availability of accurate detection systems and therapies for those biomarkers. Anaplastic ...

Jul 01, 2013
popularity not rated yet | comments 0

Scientists discover how HIV kills immune cells

Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at the National ...

Jun 05, 2013
popularity 5 / 5 (3) | comments 1 | with audio podcast

Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.

This text uses material from Wikipedia licensed under CC BY-SA