New gears in your sleep clock
The circadian cycle, a long-studied factor controlling human sleep cycles, actually has two forms, one that keeps a key protein stable, and another that promotes its degradation.
Jul 12, 2018
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The circadian cycle, a long-studied factor controlling human sleep cycles, actually has two forms, one that keeps a key protein stable, and another that promotes its degradation.
Jul 12, 2018
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Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumour, while another gene promotes the tumour. This is shown in a new dissertation at UmeƄ University, ...
May 24, 2018
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Protein researchers from the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used mass spectrometry-based proteomics to uncover a number of proteins that could play a critical role ...
May 15, 2018
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Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth ...
Mar 29, 2018
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In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude ...
Feb 5, 2018
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Researchers have demonstrated the potential of a new class of drugs for the treatment of refractory chronic obstructive pulmonary disease (COPD). Incurable to date, the disease is one of the most frequent causes of death ...
Jan 15, 2018
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Purdue University researchers have developed a high-throughput method for matching kinases to the proteins they phosphorylate, speeding the ability to identify multiple potential cancer drug targets.
Sep 21, 2017
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Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...
Sep 15, 2017
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Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce ...
Jul 16, 2017
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New research overturns long-held views on a basic messaging system within living cells. Key cellular communication machinery is more regionally constrained within the cell than previously thought. The findings suggest new ...
Jun 22, 2017
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