News tagged with protein kinase

Study: Common gene mutation affects kids with autism spectrum disorders

(Medical Xpress)—Over the past decade, researchers have made great strides in identifying genes that lead to an increased risk of autism spectrum disorders (ASD), which result in a continuum of social deficits, communication ...

Autism spectrum disorders created Sep 14, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Map of substrate-kinase interactions may lead to more effective cancer drugs

(Medical Xpress) -- Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close ...

Cancer created Mar 27, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

The protein that makes us remember pain

(PhysOrg.com) -- New research by scientists in Arizona in the US has demonstrated that an enzyme makes the body remember and remain sensitive to pain after an injury has healed.

Neuroscience created May 13, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast report

Can traumatic memories be erased? Cell biology offers promise

(Medical Xpress) -- Could veterans of war, rape victims and other people who have seen horrific crimes someday have the traumatic memories that haunt them weakened in their brains? In a new study, UCLA life ...

Neuroscience created Apr 27, 2011 | popularity 5 / 5 (6) | comments 8 | with audio podcast

Transcription factors regulating blood oxygen linked to melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0 | with audio podcast

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...

Cancer created Apr 15, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

p38beta MAPK not critical to brain inflammation, study finds

(Medical Xpress)—A study by a leading Alzheimer's researcher at the University of Kentucky provides new evidence that will help researchers home in on the molecular mechanisms involved in inflammation of the central nervous ...

Medical research created Feb 19, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study finds possible link between diabetes and increased risk of heart attack death

Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart ...

Cardiology created Feb 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

The good side of the prion: A molecule that is not only dangerous, but can help the brain grow

A few years ago it was found that certain proteins, the prions, when defective are dangerous, as they are involved in neurodegenerative syndromes such as the Creutzfeldt-Jakob and the Alzheimer diseases. ...

Medical research created Feb 14, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Trapping malaria parasites inside host cell basis for new drugs

One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...

Medical research created Jan 16, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Discovery promises to improve drugs used to fight cancer, other diseases

(Medical Xpress)—Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly ...

Medical research created Jan 11, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Cellular fuel gauge may hold the key to restricting cancer growth

Researchers at McGill University have discovered that a key regulator of energy metabolism in cancer cells known as the AMP-activated protein kinase (AMPK) may play a crucial role in restricting cancer cell growth. AMPK acts ...

Cancer created Dec 27, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports

(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...

Cancer created Dec 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel test identifies patients most likely to benefit from ALK inhibition therapy

Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...

Medical research created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists discover mechanism that could reduce obesity

Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic ...

Medical research created Dec 05, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.

For more information about Protein kinase, read the full article at Wikipedia.
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