When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...
Jun 3, 2019
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Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells. When hematopoietic stem cells mutate in specific ways, the ...
Sep 12, 2018
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Long periods of waking can lead to cognitive impairment, and the need to sleep continues to build up. Sleep then refreshes the brain through alterations in molecular biochemistry. These changes impact neuronal plasticity ...
Jun 13, 2018
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Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth ...
Mar 29, 2018
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A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond ...
Mar 6, 2018
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InSysBio continues to investigate the mechanisms underlying Alzheimer's disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. The QSP model describing the tau protein was published in PLOS ONE.
Feb 28, 2018
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Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Aug 8, 2017
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A new study has identified novel mechanisms whereby T cells may be able to distinguish an emerging class of targets specifically increased on cancer cells.
Apr 13, 2017
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In a new study by Sanford Burnham Prebys Medical Discovery Institute (SBP), researchers have identified a novel kinase cascade that regulates mTORC1, a protein complex implicated in the control of cancer cell growth in response ...
Aug 14, 2015
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A new chemical messenger that is critical in protecting the brain against Parkinson's disease has been identified by scientists at the Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit at the ...
Mar 27, 2014
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