Pick's disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65. The condition causes changes in personality, behavior and sometimes ...
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Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age. A new study by researchers at Washington University School of Medicine in St. Louis shows that the disease both starts ...
Apr 17, 2024
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In experiments with lab-grown brain cells and mouse models, scientists at Johns Hopkins Medicine say they have discovered that a cell surface protein called Lag3 is not only a biological target for FDA-approved drugs that ...
Feb 23, 2024
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With a newly developed mouse model that more accurately represents human infection with COVID-19, Johns Hopkins scientists say they have found long-term infection with SARS-CoV-2 results in brain deposits of clumped and tangled ...
Feb 23, 2024
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The tau protein accumulates in abnormal shapes in the brains of individuals with Alzheimer's disease (AD), but the early steps of tau misfolding and aggregation are unknown.
Jan 22, 2024
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The effects of Alzheimer's disease are devastating: not being able to recognize loved ones, losing precious memories, losing the ability to perform simple tasks, suffering through mood swings, and so on. Not only are memory ...
Jan 18, 2024
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Common neuropsychiatric symptoms that doctors see in Alzheimer's disease patients originate from brain inflammation rather than amyloid and tau proteins, report University of Pittsburgh School of Medicine researchers in JAMA ...
Nov 27, 2023
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For the first time, University of Queensland (UQ) researchers have shown how the tau protein, known for its role in dementias, behaves where communication in the brain takes place.
Nov 15, 2023
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An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer's disease, researchers from Yale School of Medicine and Johns Hopkins University report.
Nov 6, 2023
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Under normal circumstances, tau protein is part of the brain's infrastructure, important for stabilizing neurons into their proper shapes. But sometimes tau gets knotted up into tangles and turns toxic, injuring brain tissue ...
Sep 21, 2023
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