Haemodialysis works for reducing dabigatran levels: Implications for urgent use during bleeding or surgery
Dabigatran is one of the new oral anticoagulants which are increasingly used to prevent thrombosis. In case of an emergency (e.g. bleeding or urgent surgery), there are - despite the lack of a specific antidote - effective ...
Cardiology
Apr 08, 2013 |
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Cellular gatekeepers do more than open doors for drugs, study finds
(Medical Xpress)—The cellular gatekeepers that escort the most common pharmaceuticals into our cells continue to work within the cells as well, according to a UC San Francisco discovery that could transform drug design ...
Medical research
Apr 08, 2013 |
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Retinoic acid gradient visualized for the first time in an embryo
In a ground-breaking study, researchers from the RIKEN Brain Science Institute in Japan report a new technique that allows them to visualize the distribution of retinoic acid in a live zebrafish embryo, in ...
Medical research
Apr 07, 2013 |
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Highly lethal Ebola virus has diagnostic Achilles' heel for biothreat detection, scientists say
By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute's highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in ...
Medical research
Apr 05, 2013 |
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Protein that takes care of our DNA is critical to leukaemia cell survival
A protein – already known to be involved in a cell's response to stress – called Tetratricopeptide repeat domain 5 (TTC5) is critical to the development of acute myeloid leukaemia (AML), according to ...
Cancer
Apr 05, 2013 |
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Study reveals that chemotherapy works in an unexpected way
It's generally thought that anticancer chemotherapies work like antibiotics do, by directly killing off what's harmful. But new research published online on April 4 in the Cell Press journal Immunity shows that effective chemot ...
Immunology
Apr 04, 2013 |
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Genetic markers ID second Alzheimer's pathway
Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.
Alzheimer's disease & dementia
Apr 04, 2013 |
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A protein enables cardiovascular risk assessment
Researchers at the Charité – Universitätsmedizin Berlin have managed to predict the probability of a cardiovascular patient suffering a heart attack, stroke or arterial occlusion within three months. In the long-term, ...
Cardiology
Apr 04, 2013 |
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Researchers develop new system to study trigger of cell death in nervous system
(Medical Xpress)—Researchers at the University of Arkansas have developed a new model system to study a receptor protein that controls cell death in both humans and fruit flies, a discovery that could lead to a better understanding ...
Medical research
Apr 03, 2013 |
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Scientists identify first potentially effective therapy for human prion disease
Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations ...
Medical research
Apr 03, 2013 |
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Phase 1 ALS trial is first to test antisense treatment of neurodegenerative disease
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis (ALS) – blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease – may ...
Neuroscience
Apr 03, 2013 |
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Accused of complicity in Alzheimer's, amyloid proteins may be getting a bad rap
Amyloids—clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders—are the quintessential bad boys of neurobiology. They're thought to muck up the seamless ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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Researchers develop universal flu vaccine: New technology could become available to consumers within a decade
(Medical Xpress)—Flu is unpredictable. Influenza viruses are constantly changing—from one season to the next or even within the course of a flu season—making vaccine development difficult.
Medical research
Apr 03, 2013 |
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Research reveals how antibodies neutralize mosquito-borne virus
Researchers have learned the precise structure of the mosquito-transmitted chikungunya virus pathogen while it is bound to antibodies, showing how the infection is likely neutralized.
Medical research
Apr 02, 2013 |
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Vitamin P as a potential approach for the treatment of damaged motor neurons
Biologists from the Ruhr-Universität Bochum have explored how to protect neurons that control movements from dying off. In the journal Molecular and Cellular Neuroscience they report that the molecule 7,8-Dihydroxyflavone, also k ...
Medical research
Apr 02, 2013 |
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