Medications

PPI use is negative prognostic marker in urothelial cancer

(HealthDay)—For patients with advanced urothelial cancer treated with atezolizumab, proton pump inhibitor (PPI) use is a negative prognostic marker, according to a study published online Sept. 15 in Clinical Cancer Research.

Diseases, Conditions, Syndromes

Risk for COVID-19 increased for adults taking PPIs

(HealthDay)—Adults taking proton pump inhibitors (PPIs) have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint ...

Medical research

Newly discovered mechanism can explain increased risk of dementia

Millions of people around the world use proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that the long-term use of these drugs could ...

Gastroenterology

Suppressing stomach acid may up intestinal growth of MDROs

(HealthDay)—Stomach acid suppression medications increase the odds of intestinal colonization with multidrug-resistant microorganisms (MDROs), according to a review and meta-analysis recently published in JAMA Internal ...

Medications

Acid reflux drugs linked to increased fracture risk in kids

Proton pump inhibitors—a widely used class of drugs used to treat acid reflux and related symptoms—may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology ...

Medications

New drug combination may improve cold sore treatment

Research from Kent's School of Biosciences and the Goethe-University Frankfurt am Main, has found a drug combination that may improve treatment for diseases caused by herpes simplex viruses such as cold sore, genital herpes, ...

Oncology & Cancer

Use of PPIs tied to cognitive issues in breast cancer survivors

(HealthDay)—Use of acid reflux drugs (proton pump inhibitors [PPIs]) during and after cancer treatment may be tied to impaired memory and concentration in breast cancer survivors, according to a study recently published ...

Medications

Potential new heartburn drug studied at VUMC

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor ...

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