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News tagged with pten gene


Particular DNA changes linked with prostate cancer development and lethality

A new analysis has found that the loss or amplification of particular DNA regions contributes to the development of prostate cancer, and that patients with two of these DNA changes have a high likelihood of dying from the ...

Cancer created Apr 22, 2013 | popularity not rated yet | comments 0

Two new genetic mutations associated with Cowden syndrome

Cleveland Clinic researchers from the Lerner Research Institute have uncovered two new genes associated with Cowden syndrome (CS) according to a new study, published today in the online version of the American Journal of ...

Genetics created Dec 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Combined RB and PTEN loss identifies DCIS primed for invasive breast cancer

The combined loss of two tumor suppressor genes, retinoblastoma (RB) and phosphatase and tensin homolog (PTEN) was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published ...

Cancer created Nov 28, 2012 | popularity not rated yet | comments 0

Tumor suppressor genes vital to regulating blood precursor cells in fruit flies

UCLA stem cell scientists have shown that two common tumor suppressor genes, TSC and PTEN, are vital to regulating the stem cell-like precursor cells that create the blood supply in Drosophila, the common fruit fly.

Medical research created Sep 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers uncover new operations of cancer suppressor

(Medical Xpress) -- Scientists at the University of Dundee studying an important tumour suppressor, which is involved in at least a quarter of all cancers, have uncovered new ways in which it works.

Cancer created Feb 24, 2012 | popularity 5 / 5 (1) | comments 0

New research sheds light on gene destruction linked to aggressive prostate cancer

Researchers at Queen's University in Kingston, Canada have identified a possible cause for the loss of a tumour suppressor gene (known as PTEN) that can lead to the development of more aggressive forms of prostate cancer.

Cancer created Jan 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Cleveland Clinic researcher discovers genetic cause of thyroid cancer

Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women.

Cancer created Dec 23, 2011 | popularity not rated yet | comments 0

Study identifies genes that may help predict response to BRAF inhibitors for advanced melanoma

Genetic analysis of the tumors from patients with advanced melanoma can clue researchers in to how well patients will respond to a therapy that targets the growth-promoting protein called BRAF, a researcher from the Perelman ...

Cancer created Jun 01, 2011 | popularity not rated yet | comments 0