The key genetic events responsible for initiating the early stages of a type of childhood leukaemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the 'founder' genetic mutation ...
Apr 5, 2018
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Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that cells lacking the tumor-suppressor protein PTEN—a feature of many cancers— are particularly vulnerable to drugs that impair their energy-producing ...
Apr 3, 2018
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PTEN is best known as a tumor suppressor, a type of protein that protects cells from growing uncontrollably and becoming cancerous. But according to a new study from Columbia University Medical Center (CUMC), PTEN has a second, ...
Dec 12, 2017
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New research represents a promising step towards better understanding of a key cancer gene. A long-running collaboration between researchers at the Babraham Institute, Cambridge and the AstraZeneca IMED Biotech Unit reveals ...
Oct 19, 2017
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A year and half after losing his battle against brain cancer, Chad Carr's legacy lives through research that will help other children facing the same cruel disease.
Sep 14, 2017
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A collaboration between Saïd M. Sebti, Ph.D., chair of Moffitt Cancer Center's Drug Discovery Department, and Michele Pagano, M.D., chair of the Department of Biochemistry and Molecular Pharmacology at New York University's ...
Jun 14, 2017
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The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, Ludwig researchers have shown that one ...
May 12, 2017
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New genes which help prevent prostate, skin and breast cancer development in mice have been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators. The study identified genes that cooperate ...
Mar 20, 2017
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Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers ...
Mar 2, 2017
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Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. A study they publish today ...
Feb 13, 2017
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