Neuroscience

'Gut sense' is hardwired, not hormonal

If you've ever felt nauseous before an important presentation, or foggy after a big meal, then you know the power of the gut-brain connection.

Neuroscience

New viral tools for mapping brains

(Medical Xpress)—A brain-computer-interphase that is optogenetically-enabled is one of the most fantastic technologies we might envision today. It is likely that its full power could only be realized under the guidance ...

Diseases, Conditions, Syndromes

Dog-mediated rabies remains persistently endemic in Africa

Dog-mediated rabies, a fatal disease that kills tens of thousands of people in Africa every year, remains persistently endemic in affected regions. That is, despite an overall low virus prevalence, and attempts to combat ...

Neuroscience

Viral tool traces long-term neuron activity

For the past decade, neuroscientists have been using a modified version of the rabies virus to label neurons and trace the connections between them. Although this technique has proven very useful, it has one major drawback: ...

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Rabies

Rabies (pronounced /ˈreɪbiːz/. From Latin: rabies) is a viral neuroinvasive disease that causes acute encephalitis (inflammation of the brain) in warm-blooded animals. It is zoonotic (i.e. transmitted by animals), most commonly by a bite from an infected animal but occasionally by other forms of contact. Generally fatal if left untreated, it is a significant killer of livestock in some countries.

The rabies virus travels to the brain by following the peripheral nerves. The incubation period of the disease depends on how far the virus must travel to reach the central nervous system, usually taking a few months. Once the infection reaches the central nervous system and symptoms begin to show, the untreated infection is usually fatal within days.

Early-stage symptoms of rabies are malaise, headache and fever, later progressing to more serious ones, including acute pain, violent movements, uncontrolled excitement, depression and inability to swallow water. Finally, the patient may experience periods of mania and lethargy, followed by coma. The primary cause of death is usually respiratory insufficiency.

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