News tagged with radiation oncology

New drug enhances radiation treatment for brain cancer in preclinical studies

A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma ...

Cancer created May 14, 2013 | popularity 5 / 5 (2) | comments 0

Genetic test helps predict risk of prostate cancer recurrence

(Medical Xpress)—Prostate cancer ranks as the most common internal malignancy diagnosed in men in the United States, but often does not require extensive treatment.

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Compound in grapes, red wine could be key to fighting prostate cancer

Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University ...

Cancer created Nov 10, 2012 | popularity 5 / 5 (6) | comments 5 | with audio podcast

ASTRO and AUA issue joint guideline for radiation therapy after prostatectomy

The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) are pleased to announce the publication of the joint guideline on radiation therapy after prostatectomy for patients with and ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

VEGF may not be relevant biomarker for advanced prostate cancer

The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University ...

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0

PARP inhibitors may have clinical utility in HER2-positive breast cancers

Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Curry spice component may help slow prostate tumor growth

Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...

Cancer created Feb 10, 2012 | popularity 4.5 / 5 (10) | comments 0 | with audio podcast

New technique sheds light on RNA: Researchers develop method that could enhance gene sequencing data

Researchers at the University of Michigan Comprehensive Cancer Center have developed a technique to better understand why RNA may be different in cancer cells than in normal cells. The technique will bring new depth of understanding ...

Medical research created Jan 28, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Small molecules in the blood might gauge radiation effects after exposure

Ohio State University cancer researchers have identified molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation.

Cancer created Feb 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

LIFR protein suppresses breast cancer metastasis

A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...

Cancer created Sep 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

DCIS Score quantifies risk of ipsilateral breast event

The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to ...

Cancer created May 02, 2013 | popularity not rated yet | comments 0

After chest radiation, girls at greater risk for early breast cancer: study

(HealthDay) -- Girls who receive radiation to the chest to treat childhood cancer, even those getting lower doses, have a high risk of developing breast cancer at a young age, according to a new study.

Cancer created Jun 04, 2012 | popularity not rated yet | comments 0

Hepatic function testing can assist in treatment planning for liver cancer patients

Monitoring the hepatic function of unresectable liver cancer patients, measured by 99mTc-labeled iminodiacetic acid (HIDA) via single-photon emission computed tomography (SPECT) prior to and during radiation therapy, provides ...

Cancer created Feb 08, 2013 | popularity not rated yet | comments 0

Proscar won't boost prostate cancer survival, study finds

(HealthDay)—Men with prostate cancer taking the drug finasteride (Proscar) don't survive longer than similar men not taking the drug, a new study finds.

Cancer created Feb 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Radiation treatment transforms breast cancer cells into cancer stem cells

Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy.

Cancer created Feb 13, 2012 | popularity not rated yet | comments 0

Radiation therapy

Radiation therapy (also radiotherapy or radiation oncology, sometimes abbreviated to XRT) is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis). Radiotherapy may be used for curative or adjuvant cancer treatment. It is used as palliative treatment (where cure is not possible and the aim is for local disease control or symptomatic relief) or as therapeutic treatment (where the therapy has survival benefit and it can be curative). Total body irradiation (TBI) is a radiotherapy technique used to prepare the body to receive a bone marrow transplant. Radiotherapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, prevention of keloid scar growth, and prevention of heterotopic ossification. The use of radiotherapy in non-malignant conditions is limited partly by worries about the risk of radiation-induced cancers.

Radiotherapy is used for the treatment of malignant tumors (cancer), and may be used as the primary therapy. It is also common to combine radiotherapy with surgery, chemotherapy, hormone therapy or some mixture of the three. Most common cancer types can be treated with radiotherapy in some way. The precise treatment intent (curative, adjuvant, neoadjuvant, therapeutic, or palliative) will depend on the tumour type, location, and stage, as well as the general health of the patient.

Radiation therapy is commonly applied to the cancerous tumour. The radiation fields may also include the draining lymph nodes if they are clinically or radiologically involved with tumour, or if there is thought to be a risk of subclinical malignant spread. It is necessary to include a margin of normal tissue around the tumour to allow for uncertainties in daily set-up and internal tumor motion. These uncertainties can be caused by internal movement (for example, respiration and bladder filling) and movement of external skin marks relative to the tumour position.

To spare normal tissues (such as skin or organs which radiation must pass through in order to treat the tumour), shaped radiation beams are aimed from several angles of exposure to intersect at the tumour, providing a much larger absorbed dose there than in the surrounding, healthy tissue.

For more information about Radiation therapy, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.