News tagged with radiation oncology

LIFR protein suppresses breast cancer metastasis

A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...

Cancer created Sep 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Small molecules in the blood might gauge radiation effects after exposure

Ohio State University cancer researchers have identified molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation.

Cancer created Feb 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Proscar won't boost prostate cancer survival, study finds

(HealthDay)—Men with prostate cancer taking the drug finasteride (Proscar) don't survive longer than similar men not taking the drug, a new study finds.

Cancer created Feb 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

New technique sheds light on RNA: Researchers develop method that could enhance gene sequencing data

Researchers at the University of Michigan Comprehensive Cancer Center have developed a technique to better understand why RNA may be different in cancer cells than in normal cells. The technique will bring new depth of understanding ...

Medical research created Jan 28, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Lung cancer patients live longer if they use beta-blockers while receiving radiotherapy

Patients with non-small-cell lung cancer survive longer if they are taking beta-blockers while receiving radiotherapy, according to a study of 722 patients published in the cancer journal Annals of Oncology today.

Cancer created Jan 08, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers discover new pathways that drive metastatic prostate cancer

Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...

Cancer created Dec 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

PRT versus IMRT toxicity in Medicare beneficiaries with prostate cancer

There is no difference between proton radiotherapy (PRT) and intensity-modulated radiotherapy (IMRT) when comparing the toxicity among Medicare beneficiary patients with prostate cancer at 12 months post-treatment according ...

Cancer created Dec 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Pathway identified in human lymphoma points way to new blood cancer treatments

A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.

Cancer created Nov 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Compound in grapes, red wine could be key to fighting prostate cancer

Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University ...

Cancer created Nov 10, 2012 | popularity 5 / 5 (6) | comments 5 | with audio podcast

Older breast cancer patients see more complications with brachytherapy

heralded for its low complication rates—actually results in more complications than whole-breast radiation one year after treatment, Yale School of Medicine researchers report in the October issue of the Journal of Clinical On ...

Cancer created Oct 22, 2012 | popularity not rated yet | comments 0 | with audio podcast

Oropharyngeal cancer patients with human papillomavirus have more robust response to radiation therapy

(Medical Xpress)—UC Davis cancer researchers have discovered significant differences in radiation-therapy response among patients with oropharyngeal cancer depending on whether they carry the human papillomavirus (HPV), ...

Cancer created Sep 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

PARP inhibitors may have clinical utility in HER2-positive breast cancers

Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Taking breaks from prostate cancer hormone therapy seems safe: study

(HealthDay)—Stop-and-start hormone-deprivation therapy for localized prostate cancer doesn't shorten overall survival compared to continuous treatments, and yields fewer side effects such as impotence and ...

Cancer created Sep 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence

A recent Phase I/II clinical trial has shown that a new combination of radiation therapies developed at Virginia Commonwealth University Massey Cancer Center escalates radiation doses to safely and effectively treat prostate ...

Cancer created Jun 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Pre-op treatments boost survival for esophageal cancer patients: study

(HealthDay) -- Patients with esophageal cancer who receive chemotherapy and radiation before surgery have better outcomes, Dutch researchers report.

Cancer created May 30, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Radiation therapy

Radiation therapy (also radiotherapy or radiation oncology, sometimes abbreviated to XRT) is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis). Radiotherapy may be used for curative or adjuvant cancer treatment. It is used as palliative treatment (where cure is not possible and the aim is for local disease control or symptomatic relief) or as therapeutic treatment (where the therapy has survival benefit and it can be curative). Total body irradiation (TBI) is a radiotherapy technique used to prepare the body to receive a bone marrow transplant. Radiotherapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, prevention of keloid scar growth, and prevention of heterotopic ossification. The use of radiotherapy in non-malignant conditions is limited partly by worries about the risk of radiation-induced cancers.

Radiotherapy is used for the treatment of malignant tumors (cancer), and may be used as the primary therapy. It is also common to combine radiotherapy with surgery, chemotherapy, hormone therapy or some mixture of the three. Most common cancer types can be treated with radiotherapy in some way. The precise treatment intent (curative, adjuvant, neoadjuvant, therapeutic, or palliative) will depend on the tumour type, location, and stage, as well as the general health of the patient.

Radiation therapy is commonly applied to the cancerous tumour. The radiation fields may also include the draining lymph nodes if they are clinically or radiologically involved with tumour, or if there is thought to be a risk of subclinical malignant spread. It is necessary to include a margin of normal tissue around the tumour to allow for uncertainties in daily set-up and internal tumor motion. These uncertainties can be caused by internal movement (for example, respiration and bladder filling) and movement of external skin marks relative to the tumour position.

To spare normal tissues (such as skin or organs which radiation must pass through in order to treat the tumour), shaped radiation beams are aimed from several angles of exposure to intersect at the tumour, providing a much larger absorbed dose there than in the surrounding, healthy tissue.

For more information about Radiation therapy, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.