Neuroscience

Cocaine addiction traced to increase in number of orexin neurons

A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction. The study, performed ...

Cardiology

Estrogen may protect against depression after heart attack

Estrogen may protect against heart failure-related depression by preventing the production of inflammation-causing chemicals in the brain. The study is published ahead of print in the American Journal of Physiology—Heart ...

Neuroscience

An energy dense diet changes the brain and increases urge to eat

Research by Stephanie Borgland at the University of Calgary shows that giving rats unrestricted access to unhealthy foods for extended periods not only leads to obesity, but also to brain changes that makes food more attractive ...

Neuroscience

Stress regulates self-harm in rats

A stress hormone modulates compulsive biting in a rat model of self-injurious behavior (SIB), according to new research published in JNeurosci. Manipulating the activity of the brain circuitry underlying SIB could create ...

Neuroscience

Unexpected discovery gives new model for studying brain networks

The same kind of neurons can have completely different wiring diagrams in the rat and mouse, as mice lack intercellular molecular channels known as gap junctions, researchers at Karolinska Institutet report in the scientific ...

Alzheimer's disease & dementia

New tools could uncover important answers for Alzheimer's researchers

Alzheimer's disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer's Association. Characterized by a buildup of plaque in the brain, few animal ...

Neuroscience

Overdose antidote promotes stroke recovery in rats

The life-saving drug used to treat opioid overdose, naloxone, reduces brain inflammation in the aftermath of stroke in male rats. The preclinical research, published in eNeuro, lays the groundwork for developing the first ...

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