News tagged with rearrangement
Advances in molecular testing offer new hope for lung cancer patients
The emergence of molecular diagnostic testing in lung cancer offers new hope for patients battling the number one cancer killer in the United States and abroad. Now, for the first time after a decade of biomarker testing ...
Cancer
Apr 03, 2013 |
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Autism linked to increased genetic change in regions of genome instability
(Medical Xpress)—Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published ...
Autism spectrum disorders
Apr 03, 2013 |
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Study shows immunohistochemistry is reliable screening tool for ALK rearrangement
Favorable results have led to crizotinib gaining approval for the treatment of advanced stage ALK-positive non-small cell lung cancer (NSCLC) in Japan, the United States, Canada, and several other countries in Europe and ...
Cancer
Dec 15, 2012 |
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Study shows different approach after progression in non-small cell lung cancer patients
Right now, the best known treatment for patients with metastatic non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase gene rearrangements (ALK) or epidermal growth factor receptor mutations (EGFR) is crizotinib ...
Cancer
Nov 15, 2012 |
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Whole genome sequencing of de novo balanced rearrangements in prenatal diagnosis
Whole genome sequencing of the DNA code of three prenatal samples provided a detailed map of the locations of their chromosomal abnormalities in 14 days, scientists reported today at the American Society of Human Genetics ...
Genetics
Nov 07, 2012 |
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Crizotinib reduces tumor size in patients with ALK positive lung cancer
Crizotinib is effective in shrinking tumors in patients with anaplastic lymphoma receptor tyrosine kinase (ALK) positive non-small cell lung cancer, a cancer commonly found in people who never smoked, and should be the standard ...
Cancer
Sep 06, 2012 |
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Scientists unravel role of fusion gene in prostate cancer
Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill ...
Cancer
May 22, 2012 |
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Identical twins reveal mechanisms behind aging
In a recent study led by Uppsala University, the researchers compared the DNA of identical (monozygotic) twins of different age. They could show that structural modifications of the DNA, where large or small DNA segments ...
Genetics
Feb 02, 2012 |
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Researchers find genetic rearrangements driving 5 to 7 percent of breast cancers
Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers.
Cancer
Nov 20, 2011 |
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Genomic catastrophe causes developmental delay, cognitive disorders
Using a diversity of DNA sequencing and human genome analytic techniques, researchers led by Baylor College of Medicine have identified some cases of developmental delay or cognitive disorders associated with a sudden chromosomal ...
Genetics
Sep 15, 2011 |
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