When a woman becomes pregnant, her levels of estriol, one of the three common estrogens that are nearly undetectable before conception, skyrocket. However, scientists never knew what this hormone does or why levels of it ...
May 5, 2022
0
90
Sex hormones play an important role in shaping an animal's behavior, and their influence starts early. Early-life hormonal surges help shape the developing brain, establishing circuitry that will influence behavior for a ...
May 4, 2022
0
96
The molecular processes caused by a TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) gene mutation in the brain's microglia immune cells can increase the risk of Alzheimer's disease, according to a recent study led ...
Mar 23, 2022
0
8
The first FDA-approved gene therapies are living drugs: immune cells taken from cancer patients engineered to target tumor cells. However, for many patients, these advanced therapies do not result in a long-lasting remission. ...
Mar 16, 2022
0
95
The serotonin 2A (5-HT2A) receptor is widely distributed in the brain and plays a critical role in perception, cognition and psychosis. It is also responsible for the psychedelic effects of drugs, such as psilocybin (hallucinogenic ...
Jan 11, 2022
0
334
In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death. However, some mechanisms of this debilitating chronic respiratory disease are yet to be identified. ...
Dec 14, 2021
0
65
Gene expression is a highly regulated sequence with many players, one being the estrogen receptor-α (ER), which moves this process along by responding to hormones produced by the endocrine system. When something disrupts ...
Nov 12, 2021
0
5
Think about how often we sense touch or temperature. Perhaps its the warmth we feel when we hold a coffee cup, or the comfort we feel when hugging a loved one—these sensations are integral to our everyday lives and how ...
Oct 5, 2021
0
12
A study published in the journal Pharmacological Research describes the existence of a complex built by dopamine and noradrenergic receptors that could be a therapeutic target of potential interest to tackle the attention ...
Sep 23, 2021
0
17
New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the ...
Sep 16, 2021
0
65
