New medication offers hope to patients with frequent, uncontrollable seizures
A new type of anti-epilepsy medication that selectively targets proteins in the brain that control excitability may significantly reduce seizure frequency in people whose recurrent seizures have been resistant to even the ...
Neuroscience
Apr 18, 2012 |
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Scientists tailor cell surface targeting system to hit organelle ZIP codes
Scientists who developed a technology for identifying and targeting unique protein receptor ZIP Codes on the cellular surface have found a way to penetrate the outer membrane and deliver engineered particles - called iPhage ...
Medical research
Apr 17, 2012 |
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Eliminating the 'good cholesterol' receptor may fight breast cancer
Removing a lipoprotein receptor known as SR-BI may help protect against breast cancer, as suggested by new findings presented at the American Association for Cancer Research Annual Meeting 2012 by Jefferson's Kimmel Cancer ...
Cancer
Apr 03, 2012 |
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New research finds cause of morphine side effects
A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...
Medical research
Apr 02, 2012 |
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PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
Cancer
Apr 01, 2012 |
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Early clinical data show galeterone safe, effective against prostate cancer
Patients with castration-resistant prostate cancer had limited side effects and in many cases a drop in prostate-specific antigen expression with galeterone (TOK-001), a small-molecule oral drug, according to phase I data ...
Cancer
Apr 01, 2012 |
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Study solves structure of 'salvia receptor', reveals how salvinorin A interacts with it
At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body. Salvin ...
Medical research
Mar 21, 2012 |
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Breaking the backbone of triple-negative breast cancers
Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study published on March 19th in the Journal of Experimental Medicine.
Cancer
Mar 19, 2012 |
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Solving the mystery of blood clotting
How and when our blood clots is one of those incredibly complex and important processes in our body that we rarely think about. If your blood doesn't clot and you cut yourself, you could bleed to death, if ...
Medical research
Mar 19, 2012 |
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New universal platform for cancer immunotherapy developed
(Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T c ...
Cancer
Mar 05, 2012 |
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Perception and preference may have genetic link to obesity
About five years ago, animal studies first revealed the presence of entirely novel types of oral fat sensors or receptors on the tongue. Prior to this time, it was believed that fats were perceived only by flavor and texture ...
Health
Mar 05, 2012 |
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A culprit behind brain tumor resistance to therapy
Persistent protein expression may explain why tumors return after therapy in glioblastoma patients, according to a study published on March 5th in the Journal of Experimental Medicine.
Cancer
Mar 05, 2012 |
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Promising new compound for treating stroke
Researchers at the University of Copenhagen have designed, produced and patented a new chemical compound for the possible treatment of brain damage caused by stroke. The compound binds 1,000 times more effectively to the ...
Medical research
Feb 21, 2012 |
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Scientists create molecular map to guide treatment of multiple sclerosis
A team of scientists from the Scripps Research Institute, collaborating with members of the drug discovery company Receptos, has created the first high-resolution virtual image of cellular structures called ...
Medical research
Feb 16, 2012 |
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Curry spice component may help slow prostate tumor growth
Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...
Cancer
Feb 10, 2012 |
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