News tagged with receptors

Related topics: cells · protein · brain · molecules · nerve cells

Researchers prevent type 1 diabetes in lab

In new research published in Endocrinology, Thomas Burris, Ph.D., chair of pharmacological and physiological science at Saint Louis University, reports that his team has found a way to prevent type I diabetes in an animal ...

Jan 20, 2015
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Terpenes inhibit liver cancer

As main component of essential oils, terpenes can inhibit the growth of different cancer cells. Researchers from the Ruhr-University Bochum headed by Prof Dr Dr Dr Hanns Hatt have analysed this process in liver cancer cells ...

Jan 19, 2015
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T cell receptor ensures Treg functionality

Misdirected immune responses that target the body's own tissue can result in diseases. regulatory T cells combat this effect by suppressing excessive immune responses and responses against our own bodies. Until now, scientists ...

Jan 08, 2015
popularity7 comments 0

Team develops prognostic test for E2F4 in breast cancer

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center (NCCC), led by Chao Cheng, PhD, have identified a gene signature ...

Jan 07, 2015
popularity11 comments 0

Genetic clue points to most vulnerable children

Some children are more sensitive to their environments, for better and for worse. Now Duke University researchers have identified a gene variant that may serve as a marker for these children, who are among society's most ...

Jan 06, 2015
popularity28 comments 1

Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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