News tagged with receptors
How serotonin receptors can shape drug effects, from LSD to migraine medication
New findings by researchers carrying out experiments at the U.S. Department of Energy Office of Science's Advanced Photon Source (APS) help explain why some drugs that interact with two kinds of human serotonin ...
Medical research
May 17, 2013 |
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Preventing blood poisoning
Peptide molecules derived from the body's natural immune system can help boost the body's defence against life-threatening blood poisoning, joint University research has uncovered.
Medical research
May 17, 2013 |
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Resistance to visceral leishmaniasis: New mechanisms involved
Researchers from CNRS, Université Toulouse III - Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 ...
Immunology
May 16, 2013 |
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Study finds genetic risk factor for knee osteoarthritis
(Medical Xpress)—A newly published paper reports that individuals with radiographic knee osteoarthritis (OA) who had a specific pattern of gene variations in the interleukin-1 receptor antagonist gene (IL1RN), which is ...
Diseases, Conditions, Syndromes
May 14, 2013 |
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Brain-imaging study links cannabinoid receptors to post-traumatic stress disorder
In a first-of-its-kind effort to illuminate the biochemical impact of trauma, researchers at NYU Langone Medical Center have discovered a connection between the quantity of cannabinoid receptors in the human brain, known ...
Psychology & Psychiatry
May 14, 2013 |
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Brain, not eye mechanisms keep color vision constant across lifespan
Cone receptors in the human eye lose their color sensitivity with age, but our subjective experience of color remains largely unchanged over the years. This ability to compensate for age-related changes in color perception ...
Cardiology
May 08, 2013 |
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Experimental drug beneficial in NIH trial to treat a rare sarcoma
(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...
Cancer
May 07, 2013 |
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Scientists find potential therapeutic target for Cushing's disease
Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Researchers identify critical link in mammalian odor detection
Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally ...
Neuroscience
May 06, 2013 |
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Effects of stress on brain cells offer clues to new anti-depressant drugs
Research from King's College London reveals the detailed mechanism behind how stress hormones reduce the number of new brain cells - a process considered to be linked to depression. The researchers identified a key protein ...
Neuroscience
May 06, 2013 |
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Cancer treatment could target inflammation in CVD
Peptide receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs, an established treatment for cancer patients, could offer a novel therapeutic approach to decrease levels of inflammation in the atherosclerotic ...
Cardiology
May 05, 2013 |
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ECE: Gene variants linked to reduced male fertility
(HealthDay)—Particular gene variants of follicle stimulating hormone (FSH) and its receptor are associated with significantly reduced fertility in men, according to a study presented at the annual European ...
Genetics
May 03, 2013 |
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Making cancer less cancerous: Blocking a single gene renders tumors less aggressive
Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that ...
Cancer
May 02, 2013 |
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Study uses Botox to find new wrinkle in brain communication
National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel ...
Medical research
May 02, 2013 |
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FDA reports Samsca may cause liver damage
(HealthDay)—After reviewing data from recent large clinical trials, the U.S. Food and Drug Administration has determined that Samsca (tolvaptan) should not be used for longer than 30 days and should not ...
Medications
May 02, 2013 |
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Receptor (biochemistry)
In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.
For more information about Receptor (biochemistry), read the full article at
Wikipedia.
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