Cortisol, also commonly known as the stress hormone, belongs to the family of glucocorticoids. In addition to its physiological function, synthetic derivatives of cortisol are also used as anti-inflammatory drugs. In the ...
Mar 26, 2024
0
5
For patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-specific antigen, in addition to the wild-type ...
Mar 23, 2024
0
2
Chimeric antigen receptor T cells—CAR T cells for short—are immune cells (T cells) that are taken from the body and genetically modified outside the body in the laboratory using transport vehicles for the genes to be ...
Mar 22, 2024
0
0
Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell ...
Mar 21, 2024
0
23
Using data from both mice and humans, a Johns Hopkins Medicine research team has found that a cell surface protein that senses odors and chemicals may be responsible for—and help explain—sex differences in mammalian blood ...
Mar 20, 2024
0
7
Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein. Scientists at St. Jude Children's ...
Mar 19, 2024
0
55
The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One of the insulin-regulated processes is the quality control of mitochondria in neurons, Angelika Harbauer and her ...
Mar 19, 2024
0
70
Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
Mar 19, 2024
0
47
Polyphenols are powerful plant metabolites known for their antioxidant properties, offering potential health benefits and protection against various diseases. With over 8,000 identified varieties, these substances are found ...
Mar 18, 2024
0
9
The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
Mar 18, 2024
0
20
