News tagged with receptors

Related topics: cells · protein · brain · molecules · nerve cells

Breast cancer drug beats superbug

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling ...

Oct 13, 2015
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New treatment approved for soft-tissue cancers

(HealthDay)—Lartruvo (olaratumab) has been approved by the U.S. Food and Drug Administration to treat adults with certain soft-tissue sarcomas, cancers that develop in areas such as the muscles, fat, blood vessels and tendons.

Oct 19, 2016
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Research links fatty liver disease to type 2 diabetes

Insulin resistance in the liver is a major factor in the development of type 2 diabetes, and it is almost always associated with too much fat in the liver—a condition called non-alcoholic fatty liver disease (NAFLD). The ...

Oct 18, 2016
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Estrogen signaling impacted immune response in cancer

While the role of estrogen signaling in tumor development is well understood in breast and ovarian cancer, its role in anti-tumor immunity has not been extensively studied. However, new research from The Wistar Institute ...

Oct 17, 2016
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The secret of the learning brain

As we learn, something must change in our brain to store the information. Precisely what it is that is changing, and how it does so, remains a mystery. PhD student Rémy Kusters investigated what happens, at the smallest ...

Oct 10, 2016
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Smart drug clears fat from liver and blood

Scientists of Helmholtz Zentrum München and Technische Universität München have developed a 'smart' drug that safely clears the liver of fat and prevents blood vessels from clogging up. Similar to a trojan horse, the drug ...

Oct 10, 2016
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Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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