Oncology & Cancer

Advanced prostate cancer antibody drug shows success in pet dogs

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, ...

Oncology & Cancer

How immune cells in the tumor microenvironment make things worse

Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...

HIV & AIDS

Oral health in HIV+ population

Pushpa Pandiyan, associate professor of biological sciences in the School of Dental Medicine, and a team of researchers have been working to discover the cause behind residual systemic inflammation and dysfunction of the ...

Oncology & Cancer

A little radiation goes a long way in heating up cold tumors

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold" tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can ...

Oncology & Cancer

Increasing the immune system's appetite for cancer protectors

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, ...

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