News tagged with resistance mechanisms
New study identifies unique mechanisms of antibiotic resistance
As public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms ...
Diseases, Conditions, Syndromes
Mar 26, 2013 |
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To fight incurable metastatic breast cancer, resistance must be broken
One of the most frustrating truths about cancer is that even when a treatment works, it often doesn't work for long because cancer cells find ways to resist. However, researchers reporting studies done in mice in the December ...
Cancer
Dec 10, 2012 |
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Research may explain why some people with schizophrenia do not respond to treatment
(Medical Xpress)—New research suggests that the molecular mechanism leading to schizophrenia may be different in patients who fail to respond to anti-psychotic medication compared to patients who do respond.
Psychology & Psychiatry
Nov 29, 2012 |
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Drug resistance biomarker could improve cancer treatment
Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published ...
Cancer
Nov 21, 2012 |
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Research shows diabetes drug improves memory
An FDA-approved drug initially used to treat insulin resistance in diabetics has shown promise as a way to improve cognitive performance in some people with Alzheimer's disease.
Neuroscience
Nov 20, 2012 |
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Researcher investigate 2-drug synergy to treat drug-resistant chronic myeloid leukemia
(Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together ...
Cancer
Oct 24, 2012 |
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Researchers find cause of chemotherapy resistance in melanoma
Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.
Cancer
Sep 17, 2012 |
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Researchers find success with new immune approach to fighting some cancers
A national research collaboration of senior researchers, including a researcher from Moffitt Cancer Center, has found that 20 to 25 percent of "heavily pre-treated" patients with a variety of cancers who enrolled in a clinical ...
Cancer
Jun 13, 2012 |
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Culprit behind unchecked angiogenesis identified
German researchers unravel a critical regulatory mechanism controlling blood vessel growth that might help solve drug resistance problems in the future.
Medical research
Mar 29, 2012 |
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Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
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Combination of everolimus and exemestane improves survival for women with metastatic breast cancer
In an international Phase III randomized study, everolimus, when combined with the hormonal therapy exemestane, has been shown to dramatically improve progression-free survival, according to research from The University of ...
Cancer
Dec 08, 2011 |
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Targeting bacterial gas defenses allow for increased efficacy of numerous antibiotics
Although scientists have known for centuries that many bacteria produce hydrogen sulfide (H2S) it was thought to be simply a toxic by-product of cellular activity. Now, researchers at NYU School of Medicine have discovered ...
Medical research
Nov 17, 2011 |
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Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity
The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes ...
Medical research
Sep 29, 2011 |
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Newly discovered cell mechanism uses amplified nitric oxide to fight C. diff
Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that ...
Diseases, Conditions, Syndromes
Aug 21, 2011 |
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Copper reduces infection risk by more than 40 percent
Professor Bill Keevil, Head of the Microbiology Group and Director of the Environmental Healthcare Unit at the University of Southampton, has presented research into the mechanism by which copper exerts its ...
Diseases, Conditions, Syndromes
Jul 01, 2011 |
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