Antibody hinders growth of Gleevec-resistant gastrointestinal tumors in lab tests
An antibody that binds to a molecule on the surface of a rare but deadly tumor of the gastrointestinal tract inhibits the growth of the cancer cells in mice, according to researchers at the Stanford University School of Medicine.
Cancer
Feb 04, 2013 |
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Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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Tuberculosis may lurk in bone marrow stem cells of infected patients, researchers say
Tuberculosis is a devastating disease that kills nearly 2 million people worldwide each year. Although antibiotics exist that can ameliorate the symptoms, the courses of therapy last for months and don't completely eradicate ...
Medical research
Jan 30, 2013 |
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Mouse study offers clues to obesity-diabetes link
(HealthDay)—Obesity and type 2 diabetes are clearly intertwined, but researchers say they've found a way to weaken the connection between the two—at least in mice.
Medical research
Dec 06, 2012 |
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MicroRNAs can convert normal cells into cancer promoters
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease.
Cancer
Nov 21, 2012 |
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Scientists identify molecular process in fat cells that influences stress and longevity
As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA ...
Medical research
Sep 26, 2012 |
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Taming physical forces that block cancer treatment
A Massachusetts General Hospital research team has identified factors that contribute to solid stress within tumors, suggesting possible ways to alleviate it, and has developed a simple way to measure such pressures.
Cancer
Sep 20, 2012 |
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Single gene cause of insulin sensitivity may offer insight for treating diabetes
(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.
Diabetes
Sep 12, 2012 |
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Neutrophils: White blood cells mediate insulin resistance
Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays ...
Medical research
Aug 05, 2012 |
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New drug candidate shows promise against cancer
Drugs containing platinum are among the most powerful and widely used cancer drugs. However, such drugs have toxic side effects, and cancer cells can eventually become resistant to them.
Cancer
Jul 11, 2012 |
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Tumor microenvironment helps skin cancer cells resist drug treatment
One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the ...
Cancer
Jul 04, 2012 |
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Apramycin shows promise against drug-resistant TB and other 'superbugs,' without hearing loss
The world needs new antibiotics to overcome the ever increasing resistance of disease-causing bacteria – but it doesn't need the side effect that comes with some of the most powerful ones now available: ...
Medical research
Jun 11, 2012 |
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Protective gene in fat cells may lead to therapeutic for Type 2 diabetes
In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes. The results may lead to a ...
Medical research
Apr 01, 2012 |
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Research confirms novel strategy in fight against infectious diseases
New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself.
Medical research
Jan 09, 2012 |
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Mystery of resistance to malaria solved in new study
(Medical Xpress) -- Malaria is a disease caused by parasites passed to humans via the bites of infected mosquitoes. Globally, the disease causes over a million deaths every year, and is especially rife in ...
Medical research
Nov 11, 2011 |
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