By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease. Over the past decade, scientists ...
Feb 19, 2024
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(HealthDay)—A genetic risk score based on 46 gene variants linked to type 2 diabetes is associated with increases in the risk of type 2 diabetes and declines in glucose control and beta-cell function, according to a study ...
Jul 30, 2013
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(HealthDay)—A polygenic risk score (PRS), developed from 95 colorectal cancer (CRC)-associated genetic risk variants, is more strongly associated with early- than late-onset cancer, especially in the absence of family history, ...
Dec 26, 2019
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As new coronavirus variants emerge and quickly spread around the globe, both the public and policymakers are faced with a quandary: Maintaining a semblance of normality, while also minimizing infections. While digital contact ...
Feb 1, 2022
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PSA screening has resulted in improved prostate cancer survival, but the high rate of diagnosis and treatment side effects raise concerns about overtreatment. In the quest to prevent overtreatment, "active surveillance" has ...
Sep 24, 2012
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New research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even possibly in healthy young adults, according to a study published in the July 6, 2016, ...
Jul 6, 2016
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Risk prediction tools that estimate future risk of heart disease and stroke may be more useful predictors of future decline in cognitive abilities, or memory and thinking, than a dementia risk score, according to a new study ...
Apr 1, 2013
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Hospitals, doctors and Medicare Advantage insurance plans that care for some of the most vulnerable patients are not reimbursed fairly by Medicare, according to recent findings in JAMA.
Feb 7, 2020
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Every year, tens thousands of men in the United States are diagnosed with low-risk prostate cancer. Most are told that they don't need treatment other than "active surveillance" to monitor their slow-growing tumors. Now, ...
Sep 16, 2019
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This week, publication of a special issue on tuberculosis (TB) begins in PLOS Medicine, advised by guest editors Richard Chaisson of Johns Hopkins University, Claudia Denkinger of the University of Heidelberg, and Mark Hatherill ...
Apr 5, 2019
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