Medications

GI bleeding up for new users of rivaroxaban

Rivaroxaban is associated with increased rates of gastrointestinal bleeding (GIB) compared with other direct oral anticoagulants, according to a study published online Oct. 12 in the Annals of Internal Medicine.

Cardiology

Levetiracetam may reduce anticoagulation effect of rivaroxaban

Levetiracetam, a commonly used medication to prevent seizures, may reduce the anticoagulation effect of oral rivaroxaban in humans. As such, clinicians should measure direct oral anticoagulant plasma levels during treatment. ...

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