Long non-coding RNAs (lncRNA) are unusual in that they don't encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers.
Apr 20, 2015
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A research team led by investigators at the National Institute on Aging at the National Institutes of Health has discovered a new gene mutation associated with ALS, amyotrophic lateral sclerosis. The mutation is involved ...
Apr 1, 2014
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St. Jude Children's Research Hospital scientists led a study showing that mutations in a gene responsible for amyotrophic lateral sclerosis (ALS) disrupt the RNA transport system in nerve cells. The findings appear in the ...
Feb 5, 2014
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Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating ...
Jul 5, 2013
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As scientists learn more about processing bodies (PBs), granules present within normal cells, they are unraveling the complex role PBs play in maintaining cellular homeostasis by regulating RNA metabolism and cell signaling. ...
May 16, 2013
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Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a common dysregulation ...
Apr 26, 2013
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Scientists at the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw investigate mice with a very precisely modified genome. Because it is possible to turn off the Dicer gene in adult mice, ...
Apr 25, 2013
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A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers report.
Mar 19, 2013
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(Medical Xpress)—A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, ...
Mar 18, 2013
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Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Mar 7, 2013
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