Diseases, Conditions, Syndromes

RNA modification may protect against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from ...

Oncology & Cancer

Sensing 'junk' RNA after chemotherapy enhances blood regeneration

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...

Medical research

How cells keep gene silencing in check

Long considered 'junk," non-coding RNAs have emerged as important regulators of diverse cellular processes, including the silencing of genes. Working in yeast, researchers from the Bühler group have identified more than ...

Psychology & Psychiatry

Inflammatory process alteration accompanies opioid use disorder

Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths—nearly 50,000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical ...

Medical research

Ageing impairs critical final egg maturation stage

Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according ...

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