Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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West Nile virus passes from female to eggs, but less so from larvae to adults
In California Culex mosquitoes are considered to be the principle vectors of West Nile virus (WNV), which infects birds, humans, and other mammals during the summer. In addition, these mosquitoes may also serve as overwintering ...
Diseases, Conditions, Syndromes
Mar 05, 2013 |
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Proteins with mutations in 'prion-like' segments considered candidates for inherited forms of ALS
A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman ...
Medical research
Mar 03, 2013 |
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Zeroing in on heart disease: Innovative strategy pinpoints genes underlying cardiovascular disease risk
Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers ...
Genetics
Feb 28, 2013 |
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Researchers find controlling element of Huntington's disease
A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Diseases, Conditions, Syndromes
Feb 26, 2013 |
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Team finds general mechanism that accelerates tumor development
ICREA professor Raúl Méndez publishes a study in Nature describing how the CPBE1 protein "takes the brakes off" the production of proteins associated with the cell switch from being healthy to tumorous. ...
Cancer
Feb 24, 2013 |
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Ыtudy documents head and neck cancer molecular tumor subtypes
Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of ...
Cancer
Feb 22, 2013 |
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New flu drug stops virus in its tracks
A new class of influenza drug has been shown effective against drug-resistant strains of the flu virus, according to a study led by University of British Columbia researchers.
Medical research
Feb 21, 2013 |
4.6 / 5 (11) |
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Computer modeling reveals how surprisingly potent hepatitis C drug works
A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its ...
Diseases, Conditions, Syndromes
Feb 18, 2013 |
4.8 / 5 (4) |
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Challenge to cancer gene patent fails in Australia
An Australian court Friday dismissed a challenge against the patenting of human genetic material in a landmark case which has devastated a cancer group that says it could stifle research.
Cancer
Feb 15, 2013 |
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Discovery in HIV may solve efficiency problems for gene therapy
A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients.
HIV & AIDS
Feb 14, 2013 |
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Long noncoding RNAs control development of fat cells
Whitehead Institute researchers have identified a previously unrecognized layer of genetic regulation that is necessary for the generation of undesirable white fat cells. When this regulation is disrupted, white fat cells ...
Overweight and Obesity
Feb 13, 2013 |
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Synthetic circuit allows dialing gene expression up or down in human cells
Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Co ...
Genetics
Feb 12, 2013 |
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Deep genomic analysis identifies a micro RNA opponent for ovarian cancer
Researchers employed an extensive analysis of genomic information to identify a new, high-risk cohort of ovarian cancer patients, characterize their tumors, find a potential treatment and test it in mouse models of the disease.
Cancer
Feb 11, 2013 |
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First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment
A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology (VHIO) and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first ...
Cancer
Feb 11, 2013 |
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