Study finds potential to match tumors with known cancer drugs
When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist.
Cancer
Feb 05, 2013 |
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RNA promotes metastasis in lung cancer
The vast majority – approximately 80 percent – of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied ...
Cancer
Feb 05, 2013 |
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Gene variants found to affect human lifespan
By broadly comparing the DNA of children to that of elderly people, gene researchers have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease.
Genetics
Feb 04, 2013 |
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Bioelectric signals can be used to detect early cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
Medical research
Feb 01, 2013 |
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A new mechanism that contributes to the evolution of cancer
Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to ...
Cancer
Jan 31, 2013 |
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New design guidelines simplify development of targeted therapies for muscular dystrophy and other diseases
The dystrophin protein offers critical support to muscle fibers. Mutations affecting dystrophin's expression cause the muscle-wasting disease muscular dystrophy. In Duchenne muscular dystrophy (DMD), these ...
Genetics
Jan 30, 2013 |
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Researchers find gene that turns up effect of chemotherapy
Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research ...
Cancer
Jan 29, 2013 |
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New technique sheds light on RNA: Researchers develop method that could enhance gene sequencing data
Researchers at the University of Michigan Comprehensive Cancer Center have developed a technique to better understand why RNA may be different in cancer cells than in normal cells. The technique will bring new depth of understanding ...
Medical research
Jan 28, 2013 |
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Long non-coding RNA molecules necessary to regulate differentiation of embryonic stem cells into cardiac cells
When the human genome was sequenced, biologists were surprised to find that very little of the genome—less than 3 percent—corresponds to protein-coding genes. What, they wondered, was all the rest of ...
Medical research
Jan 25, 2013 |
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Scientists identify new strategy to fight deadly infection in cystic fibrosis
New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).
Medical research
Jan 23, 2013 |
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Immune system foiled by a hairpin
The innate immune system detects invasive pathogens and activates defense mechanisms to eliminate them. Pathogens, however, employ a variety of tricks to block this process. A new study shows how the measles virus thwarts ...
Immunology
Jan 22, 2013 |
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Recent study suggests bats are reservoir for ebola virus in Bangladesh
EcoHealth Alliance, a nonprofit organization that focuses on local conservation and global health issues, released new research on Ebola virus in fruit bats in the peer reviewed journal, Emerging Infectious Diseases, a mont ...
Diseases, Conditions, Syndromes
Jan 16, 2013 |
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Hepatitis B virus promotes oncogenesis through microRNA modulation
Viruses prompt oncogenic transformation by genetically altering infected cells. Several recent studies have demonstrated that viruses alter the expression of microRNAs, non-coding RNA molecules that can block the expression ...
Diseases, Conditions, Syndromes
Jan 16, 2013 |
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Foot soldiers of the immune system: IFIT antiviral protein recognizes foreign RNA and blocks viral infections
Researchers at McGill University and the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences have discovered the molecular blueprint behind the IFIT protein. This key protein enables the human ...
Immunology
Jan 13, 2013 |
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Regulating single protein prompts fibroblasts to become neurons
Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching ...
Medical research
Jan 10, 2013 |
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