The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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Researchers identify quadruplex structure in C9ORF72
(Medical Xpress)—A Motor Neurone Disease (MND) Association funded research project at UCL has given new insights into the structure and function of an MND gene called C9ORF72. The work is published in the journal Scientific Re ...
Medical research
Dec 24, 2012 |
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Targeted gene silencing drugs are more than 500 times more effective with new delivery method
Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically ...
Medical research
Dec 21, 2012 |
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FDA panel considers 1st drug for chronic fatigue syndrome
(HealthDay)—A U.S. Food and Drug Administration advisory committee will meet Thursday to consider approval of the first drug to treat chronic fatigue syndrome.
Medications
Dec 20, 2012 |
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Mount Sinai grad student, 25, named to Forbes '30 Under 30' in Science and Healthcare
Jillian Shapiro, a third-year graduate student at the Icahn School of Medicine at Mount Sinai, has been named to the second annual Forbes "30 Under 30" list in "Science and Health." The honorees "reflect the way that the he ...
Medical research
Dec 20, 2012 |
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CNIO researchers develop new databases for understanding the human genome
Scientists from the Structural Computational Biology Group at the Spanish National Cancer Research Centre (CNIO), led by Alfonso Valencia, together with French and American researchers, have published recently two articles ...
Genetics
Dec 17, 2012 |
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Carriers of gene variant appear less likely to develop heart disease
Scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University have discovered a new gene mechanism that appears to regulate triglyceride levels. This pathway may protect carriers of ...
Genetics
Dec 14, 2012 |
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Study reveals alternative pathway through which beta-catenin drives colon cancer
Colon cancer is one of the leading causes of cancer-related death in the United States. Risk factors for the disease are varied and include factors such as advanced age and diet, but most cases share something ...
Cancer
Dec 14, 2012 |
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Researchers use microRNAs to induce regeneration of heart tissue
(Medical Xpress)—A research team working at Italy's International Centre for Genetic Engineering and Biotechnology has succeeded in causing heart tissue to regenerate by introducing two microRNAs into damaged mice hearts. ...
Medical research
Dec 06, 2012 |
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A study of fruit fly genes reveals how molecules cooperate to induce tumor formation
Cancer biologists have known for decades that even the most potent cancer-causing genes do not act alone. Yet, identifying which combinations of genetic changes can cause a tumor to form and disease to progress ...
Genetics
Dec 05, 2012 |
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Scientists discover master regulator of skin development
The surface of your skin, called the epidermis, is a complex mixture of many different cell types—each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount ...
Medical research
Dec 02, 2012 |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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Scientists uncover a novel cooperative effort to stop cancer spread
(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the ...
Cancer
Nov 28, 2012 |
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Researchers describe elusive replication machinery of flu viruses
Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy ...
Medical research
Nov 22, 2012 |
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A class of RNA molecules protects germ cells from damage, researchers show
Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.
Genetics
Nov 15, 2012 |
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