RNA interference for human therapy
Leading scientists in the field investigated the potential of RNA interference (RNAi) technology as a therapeutic intervention for down-regulating the expression of disease-associated genes. Project deliverables ...
Medical research
Sep 20, 2012 |
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In obesity, a micro-RNA causes metabolic problems
Scientists have identified a key molecular player in a chain of events in the body that can lead to fatty liver disease, Type II diabetes and other metabolic abnormalities associated with obesity. By blocking ...
Overweight and Obesity
Sep 20, 2012 |
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Novel therapy for improving airway hydration status in cystic fibrosis patients
Cystic fibrosis is one of the most common inherited single gene diseases, with an incidence of 1 out of 3,000 newborns in central Europe. An EU study developed a novel gene therapy approach for improving ...
Diseases, Conditions, Syndromes
Sep 20, 2012 |
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Gene regulation through non-coding RNAs
A number non-coding RNAs are transcribed in humans but their role in the human body has not been elucidated. European scientists are deciphering the role of such RNAs in a newly discovered imprinted human ...
Genetics
Sep 20, 2012 |
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MicroRNA derails protein that blocks insulin production
(Medical Xpress)—Work by Michigan Technological University biologist Xiaoqing Tang is yielding new insights into how a tiny snippet of genetic material can promote healthy insulin production in mice.
Medical research
Sep 20, 2012 |
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Researchers identify gene partly responsible for maternal care in mice
(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...
Genetics
Sep 18, 2012 |
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Recent findings hold new implications for the pathogenesis of myotonic dystrophy
An important breakthrough could help in the fight against myotonic dystrophy. The discovery, recently published in the prestigious scientific journal Cell, results from an international collaboration between researchers at the ...
Medical research
Sep 12, 2012 |
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ENCODE project: In massive genome analysis new data suggests 'gene' redefinition
Most people understand genes to be specific segments of DNA that determine traits or diseases that are inherited. Textbooks suggest that genes are copied ("transcribed") into RNA molecules, which are then used as templates ...
Genetics
Sep 05, 2012 |
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Binding sites for LIN28 protein found in thousands of human genes
A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which ...
Genetics
Sep 04, 2012 |
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Precise and persistent cell sabotage: Control of siRNA could aid regenerative medicine, cancer therapy
Some of the body's own genetic material, known as small interfering RNA (siRNA), can be packaged then unleashed as a precise and persistent technology to guide cell behavior, researchers at Case Western Reserve University ...
Medical research
Aug 27, 2012 |
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Researchers may have found a weak link in the flu virus
(Medical Xpress)—A team of researchers, led by scientists at the University of Rochester, has identified a location in a gene of the influenza A virus that could be used as a "switch" for disrupting replication ...
Medical research
Aug 27, 2012 |
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Field guide to the Epstein-Barr virus charts viral paths toward cancer
Researchers from The Wistar Institute and Memorial Sloan-Kettering Cancer Center (MSKCC) have teamed to publish the first annotated atlas of the Epstein-Barr virus genome, creating the most comprehensive ...
Medical research
Aug 23, 2012 |
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New nanoparticles that shut off cancer genes shrink tumors in mice
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...
Cancer
Aug 15, 2012 |
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New Genetics educational resource promotes active learning
As upper level undergraduate genetics instructors plan their syllabi for the fall semester, the Genetics Society of America's GENETICS journal offers a new educational resource, articles called "Primers." These articles are de ...
Genetics
Aug 09, 2012 |
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Using millions of years of cell evolution in the fight against cancer
As the medical community continues to make positive strides in personalized cancer therapy, scientists know some dead ends are unavoidable. Drugs that target specific genes in cancerous cells are effective, but not all proteins ...
Genetics
Aug 07, 2012 |
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