New study represents major breakthrough in macular degeneration
University of Kentucky researchers, led by Dr. Jayakrishna Ambati, have made an exciting finding in the "dry" form of age-related macular degeneration known as geographic atrophy (GA). GA is an untreatable condition that ...
Medical research
Aug 06, 2012 |
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Catching the cap-snatcher: Structural analysis opens the way to new anti-influenza drugs
Researchers at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have determined the detailed 3-dimensional structure of part of the flu virus' RNA polymerase, an enzyme that is crucial for influenza virus ...
Diseases, Conditions, Syndromes
Aug 02, 2012 |
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A genetic variation common in East Asian populations has been linked to cancer drug resistance
Tyrosine kinase inhibitors (TKIs) kill cancerous cells by inducing programmed cell death. They are of enormous therapeutic benefit to patients with chronic myeloid leukemia (CML) and certain types of lung ...
Genetics
Aug 02, 2012 |
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A step forward toward muscular dystrophy treatment: 'Antisense' compound rids muscle cells of toxic RNA
Scientists have reversed symptoms of myotonic muscular dystrophy in mice by eliminating a buildup of toxic RNA in muscle cells. The work, carried out by scientists at the University of Rochester Medical Center, Isis Pharmaceuticals ...
Medical research
Aug 01, 2012 |
4 / 5 (2) |
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The RHAU helicase: A key player in blood formation
Scientists at the Friedrich Miescher Institute for Biomedical Research have discovered that the helicase RHAU, a protein that can resolve complex structures in both DNA and RNA molecules, is essential for ...
Medical research
Jul 31, 2012 |
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Infection warning system in cells contains targets for antiviral and vaccine strategies
Two new targets have been discovered for antiviral therapies and vaccines strategies that could enhance the body's defenses against such infectious diseases as West Nile and hepatitis C. The targets are within the infection ...
Immunology
Jul 30, 2012 |
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miR-122: Loss of tiny liver molecule might lead to liver cancer
A new study shows that loss of a small RNA molecule in liver cells might cause liver cancer and that restoring the molecule might slow tumor growth and offer a new way to treat the disease.
Medical research
Jul 23, 2012 |
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Brain variants of protein associated with Huntington's and other neurodegenerative diseases identified
(Medical Xpress) -- A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research ...
Genetics
Jul 23, 2012 |
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TGen method isolates biospecimens for treatment of kidney disease
Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, ...
Diseases, Conditions, Syndromes
Jul 11, 2012 |
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Levels of hepatitis C virus higher among African-Americans and males
Epidemiologists have determined that levels of hepatitis C virus (HCV) found among injection drug users (IDUs) were higher in individuals who are male or African American even after differences in other factors were considered. ...
Diseases, Conditions, Syndromes
Jul 10, 2012 |
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What happens when we sunburn: Researchers describe inflammatory mechanism for first time
The biological mechanism of sunburn – the reddish, painful, protective immune response from ultraviolet (UV) radiation – is a consequence of RNA damage to skin cells, report researchers at the University ...
Medical research
Jul 08, 2012 |
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New compound holds promise for treating Duchenne MD, other inherited diseases
Scientists at UCLA have identified a new compound that could treat certain types of genetic disorders in muscles. It is a big first step in what they hope will lead to human clinical trials for Duchenne muscular dystrophy.
Genetics
Jun 27, 2012 |
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Enzyme offers new therapeutic target for cancer drugs
Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...
Cancer
Jun 21, 2012 |
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MicroRNAs link the pathways that control growth during animal development and in disease
Cellular mechanisms that enable healthy growth can spiral out of control and give rise to cancer. For this reason, signal transduction pathways that underlie cell growth are tightly regulated, with multiple ...
Medical research
Jun 20, 2012 |
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Abnormal gene product associated with prostate cancer generated by unusual mechanism
Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association for Ca ...
Cancer
Jun 19, 2012 |
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