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News tagged with rnai


Novel intercellular transportation system may have potential for delivering RNAi and other gene-based therapeutics

(Medical Xpress)—Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting ...

Neuroscience created Mar 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Clinical trial finds new class of cancer drugs safe and effective

The safety and preliminary efficacy of a new class of tumor fighting drugs were reported today by Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials and the Translational Genomics Research Institute (TGen).

Cancer created Apr 09, 2013 | popularity 5 / 5 (2) | comments 0

Deep genomic analysis identifies a micro RNA opponent for ovarian cancer

Researchers employed an extensive analysis of genomic information to identify a new, high-risk cohort of ovarian cancer patients, characterize their tumors, find a potential treatment and test it in mouse models of the disease.

Cancer created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0

Hedgehog pathway key in tamoxifen-resistant breast CA

(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh ...

Cancer created Nov 06, 2012 | popularity not rated yet | comments 0

Double whammy: RNAi enhances lung cancer therapy

Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors ...

Cancer created Mar 20, 2012 | popularity not rated yet | comments 0

First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment

A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology (VHIO) and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first ...

Cancer created Feb 11, 2013 | popularity 5 / 5 (2) | comments 0

CHEO scientist advances biotherapeutics as published in Cancer Cell

Oncolytic virology uses live viruses to sense the genetic difference between a tumor and normal cell. Once the virus finds a tumor cell, it replicates inside that cell, kills it and then spreads to adjacent tumor cells to ...

Cancer created Oct 18, 2011 | popularity not rated yet | comments 0