Scientists led by Sabine Taschner-Mandl, Ph.D., St. Anna Children's Cancer Research Institute, and Nikolaus Fortelny, Ph.D., Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood ...
Jun 26, 2023
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Inhibiting HDAC6 improves the structural stability of cells and protects against neuronal damage. Leuven research uncovered that targeting this mechanism could be a promising therapeutic approach for peripheral neuropathies, ...
Feb 8, 2018
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When a virus or bacteria comes calling, protein "sensors" in your cells can detect the invader's DNA and activate inflammatory responses to prevent infection. One such sensor is cGAS (cyclic GMP-AMP synthase).
Oct 13, 2017
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Cancer cells with mutations in BRCA1 or BRCA2 genes, which serve a vital role in preserving the integrity of the genetic code, are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient ...
Nov 5, 2015
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It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction ...
Apr 16, 2012
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Researchers at National University of Ireland Galway have made a significant scientific discovery in the fight against Huntington's disease. The novel findings are published 21 February in the online, open access journal ...
Feb 21, 2012
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