News tagged with signal transduction pathway


Enzyme offers new therapeutic target for cancer drugs

Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...

Cancer created Jun 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Novel AKT pathway inhibitor, ARQ 092, demonstrated safety, effective target inhibition

Researchers have confirmed that the novel oral agent ARQ 092 inhibits the AKT pathway and has a manageable safety profile in patients with a variety of advanced solid tumors, according to phase I data presented at the AACR ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Parkinson's disease: Parkin protects from neuronal cell death

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

Parkinson's & Movement disorders created Mar 01, 2013 | popularity 5 / 5 (2) | comments 0

Study confirms everolimus can overcome trastuzumab resistance in HER-2 positive early breast cancer

A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab has left researchers contemplating a puzzle.

Cancer created May 02, 2013 | popularity not rated yet | comments 0