News tagged with signaling pathway
Researchers discover gene that permanently stops cancer cell proliferation
Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without ...
Cancer
Aug 01, 2012 |
4.9 / 5 (49) |
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Primary component in turmeric kicks off cancer-killing mechanisms in human saliva
Curcumin, the main component in the spice turmeric, suppresses a cell signaling pathway that drives the growth of head and neck cancer, according to a pilot study using human saliva by researchers at UCLA's Jonsson Comprehensive ...
Cancer
Sep 13, 2011 |
5 / 5 (12) |
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New study points to major discovery for Alzheimer's disease
The Journal of Neuroscience has published a study led by researchers at the Max Planck Florida Institute for Neuroscience, the first and only U.S. extension of the prestigious Max Planck Society, that may hold a stunning breakt ...
Alzheimer's disease & dementia
Mar 19, 2013 |
4.9 / 5 (7) |
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Genes for learning, remembering, forgetting: Proteins important in embryos found to change the adult brain
Certain genes and proteins that promote growth and development of embryos also play a surprising role in sending chemical signals that help adults learn, remember, forget and perhaps become addicted, University ...
Medical research
Mar 29, 2012 |
5 / 5 (6) |
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Feeling hungry may protect the brain against Alzheimer's disease, study finds
The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger ...
Alzheimer's disease & dementia
Apr 03, 2013 |
5 / 5 (6) |
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Researcher creates neurons that light up as they fire
In a scientific first that potentially could shed new light on how signals travel in the brain, how learning alters neural pathways, and might lead to speedier drug development, scientists at Harvard have created genetically-altered ...
Neuroscience
Nov 29, 2011 |
4.8 / 5 (5) |
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Why smokers are thinner? Nicotine triggered appetite suppression site identified in brain
It is widely known that smoking inhibits appetite, but what is not known, is what triggers this process in the brain. Now researchers from Baylor College of Medicine, participating in a Yale University School of Medicine-led ...
Neuroscience
Jun 09, 2011 |
4.6 / 5 (5) |
1
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Study sheds light on how pancreatic cancer begins
A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.
Cancer
Nov 29, 2012 |
4.2 / 5 (5) |
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New gene study of ADHD points to defects in brain signaling pathways
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility ...
Attention deficit disorders
Dec 04, 2011 |
4 / 5 (5) |
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Scientists show lack of single protein results in persistent viral infection
Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the ...
Medical research
Jun 13, 2012 |
5 / 5 (4) |
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Study finds how BPA affects gene expression, anxiety; Soy mitigates effects
New research led by researchers at North Carolina State University shows that exposure to the chemical bisphenol A (BPA) early in life results in high levels of anxiety by causing significant gene expression changes in a ...
Medical research
Sep 07, 2012 |
5 / 5 (4) |
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Researchers describe how breast cancer cells acquire drug resistance
A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...
Cancer
May 07, 2013 |
5 / 5 (4) |
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Researchers develop compound to block signaling of cancer-causing protein
Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the ...
Cancer
Jul 17, 2011 |
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Structure of vital protein complex, G protein-coupled receptors, described in unprecedented detail
Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented ...
Medical research
Sep 28, 2011 |
5 / 5 (3) |
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Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Cancer
Jan 23, 2012 |
5 / 5 (3) |
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Signal transduction
In biology, 'signal transduction' refers to any process by which a cell converts one kind of signal or stimulus into another. Most processes of signal transduction involve ordered sequences of biochemical reactions inside the cell, which are carried out by enzymes and activated by second messengers, resulting in a signal transduction pathway. Such processes are usually rapid, lasting on the order of milliseconds in the case of ion flux, or minutes for the activation of protein- and lipid-mediated kinase cascades, but some can take hours, and even days (as is the case with gene expression), to complete. The number of proteins and other molecules participating in the events involving signal transduction increases as the process emanates from the initial stimulus, resulting in a "signal cascade," beginning with a relatively small stimulus that elicits a large response. This is referred to as amplification of the signal.
For more information about Signal transduction, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
