A basic science discovery by researchers at the Johns Hopkins Bloomberg School of Public Health reveals a fundamental way cells interpret signals from their environment and may eventually pave the way for potential new therapies.
Nov 20, 2020
0
20
Obesity is a serious global health problem and a risk factor for diseases such as type II diabetes, heart disease and fatty liver disease. A central element in the development of obesity is adipose tissue, which comprises ...
Nov 17, 2020
0
46
Deleting the TSC2 gene in specific lung cells of mice led to the activation of the mTORC1 signaling pathway and pulmonary disease characteristics consistent with human LAM disease, particularly in female breeder mice. These ...
Nov 9, 2020
0
221
Tumors come in many shapes and forms—curable or deadly, solid or liquid, lodged inside the brain, bone, or other tissues. One thing they all have in common, however, is a knack for molecular deceit. It is often by posing ...
Sep 30, 2020
0
109
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Sep 15, 2020
0
85
Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.
Aug 28, 2020
0
509
Our mouths may be home to a newly discovered set of multi-tasking taste cells that—unlike most known taste cells, which detect individual tastes—are capable of detecting sour, sweet, bitter and umami stimuli. A research ...
Aug 13, 2020
0
206
Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal.
Jul 14, 2020
0
4058
Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...
Jul 8, 2020
0
113
Scientists at LMU have shown that a signaling pathway that is disrupted in Ewing sarcoma specifically sensitizes tumor cells to a particular drug. The finding may open a route to new therapies for the most aggressive forms ...
May 18, 2020
0
38
