Diseases, Conditions, Syndromes

Why is herpes simplex virus disease risk so much greater for newborns?

Interferon is a crucial component of the human immune system's response to infection by herpes simplex virus type 1 (HSV-1), but how important a role it plays in determining the severity of disease and explaining why newborns ...

Diseases, Conditions, Syndromes

Scientists advance understanding of herpesvirus infection

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle ...

Diseases, Conditions, Syndromes

Routine screening for genital herpes infection not recommended

The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening (via a blood test) for genital herpes simplex virus infection in asymptomatic adolescents and adults, including those who are ...

Diseases, Conditions, Syndromes

Evidence of Zika virus found in tears

Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis. The study, in mice, helps ...

Diseases, Conditions, Syndromes

Preclinical evaluation of a vaccine against herpes viruses

Oral and genital herpes are caused by the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2), which both cause lifelong infection. HSV-2 infection is associated with increased risk for HIV infection. ...

Immunology

How antibodies access neurons to fight infection

Yale scientists have solved a puzzle of the immune system—how antibodies enter the nervous system to control viral infections. Their finding may have implications for the prevention and treatment of a range of conditions, ...

Diseases, Conditions, Syndromes

Herpes simplex virus linked to frailty, mortality

(HealthDay)—For older women, herpes simplex virus antibody levels are associated with incident frailty and mortality, according to a study published online April 30 in the Journal of the American Geriatrics Society.

Medical research

Scientists reveal new target for anti-lymphangiogenesis drugs

After an injury to tissues, such as in organ transplantation, the body grows new lymphatic vessels in a process known as lymphangiogenesis. A new study in Nature Communications reveals a mechanism involved in the regulation ...

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