Oncology & Cancer

Researchers discover how lactic acid weakens anti-tumor defenses

In cancer research, it has long been known that lactic acid, or lactate, is produced in large quantities by cancer cells and that this lactic acid disrupts our defense against tumors. Until now, however, we did not know exactly ...

Medical research

How skin cells form a first line of defense against cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer. The findings offer new clues into the behavior ...

Oncology & Cancer

Researchers find new potential targets for skin cancer treatment

Mutations of the gene MLL4 in epithelial skin cells can inhibit healthy cell turnover and may lead to keratinocyte cancers, which collectively outnumber all other human cancers. Targeting pathways altered by MLL4 mutations ...

Immunology

Suffering from psoriasis? Blame this trio of proteins

About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds ...

Medical research

The prostate cancer cell that got away

Cold Spring Harbor Laboratory (CSHL) Associate Professor Pavel Osten and Professor Lloyd Trotman have developed a new way to study the life history of prostate cancer in mice. The pair combined their expertise in whole-organ ...

Diseases, Conditions, Syndromes

Study finds the SARS-CoV-2 virus can infect the inner ear

Many COVID-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

Immunology

Mechanism behind ineffective psoriasis drugs identified

Psoriasis is a chronic inflammatory autoimmune disease that manifests as red, scaly skin patches. There is no causal treatment for the disease, but the symptoms can be significantly alleviated with modern therapies. Complex ...

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