News tagged with smallpox
A genetically-engineered virus tested in 30 terminally-ill liver cancer patients significantly prolonged their lives, killing tumours and inhibiting the growth of new ones, scientists reported on Sunday.
Cancer Feb 10, 2013 | 4.6 / 5 (44) | 12
How well people are protected by the smallpox vaccine depends on more than the quality of the vaccination: individual genes can alter their response, Mayo Clinic research shows. The findings, gathered using sophisticated ...
Genetics Apr 18, 2013 | not rated yet | 0
(HealthDay)—A man recently vaccinated for smallpox under a U.S. Defense Department program passed a milder, related form of the disease on to a man he had sex with, and that man then passed it on to yet ...
Diseases, Conditions, Syndromes Feb 28, 2013 | 5 / 5 (1) | 1 |
(AP) -- Anthrax vaccine - check. Antibiotics - check. A botulism treatment - check. Smallpox vaccine - check.
Other Sep 26, 2011 | not rated yet | 0
As part of a multicenter clinical trial, researchers at University of California, San Diego School of Medicine are evaluating Pexa-Vec (JX-594) to slow the progression of hepatocellular carcinoma (HCC) or liver cancer. Pexa-Vec ...
Cancer Apr 10, 2013 | 5 / 5 (2) | 0
Despite the many overwhelming successes of vaccines in the past century, including the eradication of smallpox and near-eradication of polio, many adults do not know how vaccines work, or even realize that the benefits of ...
Immunology Mar 14, 2012 | 5 / 5 (1) | 1
(HealthDay) -- Pre-teens living in states that require vaccinations for incoming middle school students are more likely to be immunized than those in states without such requirements, a new study finds.
Pediatrics May 07, 2012 | not rated yet | 0
The observation that milkmaids are frequently infected with cowpox but rarely catch smallpox is generally credited to the English doctor Edward Jenner. Although Jenner might not have been the first person to notice the correlation, ...
Diseases, Conditions, Syndromes Sep 14, 2011 | not rated yet | 0
Declaring the eradication of polio will be far more difficult than it was for smallpox, according to a review published in the Journal of General Virology. Further research into the complex virus - host i ...
Diseases, Conditions, Syndromes Nov 30, 2011 | not rated yet | 0
Most remaining laboratory stocks of a devastating cattle disease should be destroyed to ensure the eradicated virus is not back into nature, the World Organisation for Animal Health (OIE) said Monday.
Diseases, Conditions, Syndromes Dec 10, 2012 | not rated yet | 0
(AP) -- The pharmaceutical industry won approval to market a record number of new drugs for rare diseases last year, as a combination of scientific innovation and business opportunity spurred new treatments for diseases ...
Medications Jan 25, 2012 | 5 / 5 (1) | 0
Afghan President Hamid Karzai urged insurgents Tuesday to allow health teams to vaccinate children in war-torn parts of the country where cases of polio have risen sharply.
Diseases, Conditions, Syndromes Jan 17, 2012 | not rated yet | 0
Polio cases worldwide reached historic lows in 2012, and for the first time there were no new outbreaks beyond countries already harboring the disease, leaving researchers confident that a massive and re-energized international ...
Diseases, Conditions, Syndromes Nov 13, 2012 | not rated yet | 0
(AP)—Software magnate and philanthropist Bill Gates, who is helping spearhead a global campaign to eradicate polio, said Thursday he hopes that by 2015 no child in the world will be paralyzed by the disease and by 2018 ...
Diseases, Conditions, Syndromes Sep 27, 2012 | 5 / 5 (1) | 0
Guinea worm disease cases were cut to less than 600 in 2012, marking significant progress in eradicating the parasitic infection, former President Jimmy Carter said Thursday.
Diseases, Conditions, Syndromes Jan 17, 2013 | not rated yet | 0
Smallpox is an infectious disease unique to humans, caused by either of two virus variants, Variola major and Variola minor. The disease is also known by the Latin names Variola or Variola vera, which is a derivative of the Latin varius, meaning spotted, or varus, meaning "pimple". The term "smallpox" was first used in Europe in the 15th century to distinguish variola from the "great pox" (syphilis).
Smallpox localizes in small blood vessels of the skin and in the mouth and throat. In the skin, this results in a characteristic maculopapular rash, and later, raised fluid-filled blisters. V. major produces a more serious disease and has an overall mortality rate of 30–35%. V. minor causes a milder form of disease (also known as alastrim, cottonpox, milkpox, whitepox, and Cuban itch) which kills about 1% of its victims. Long-term complications of V. major infection include characteristic scars, commonly on the face, which occur in 65–85% of survivors. Blindness resulting from corneal ulceration and scarring, and limb deformities due to arthritis and osteomyelitis are less common complications, seen in about 2–5% of cases.
Smallpox is believed to have emerged in human populations about 10,000 BC. The disease killed an estimated 400,000 Europeans each year during the 18th century (including five monarchs), and was responsible for a third of all blindness. Of all those infected, 20–60%—and over 80% of infected children—died from the disease.
During the 20th century, it is estimated that smallpox was responsible for 300–500 million deaths. In the early 1950s an estimated 50 million cases of smallpox occurred in the world each year. As recently as 1967, the World Health Organization estimated that 15 million people contracted the disease and that two million died in that year. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the eradication of smallpox in December 1979. To this day, smallpox is the only human infectious disease to have been completely eradicated.
For more information about Smallpox, read the full article at
This text uses material from Wikipedia and is available under the GNU Free Documentation License.