Viral Vectors delivery new calcium pumps for ailing hearts
(Medical Xpress)—A fresh round of trials to evaluate gene therapy for the heart is set to begin in a couple of weeks. The British Heart Foundation will be sponsoring the study, which seeks to replace defective ...
Medical research
May 01, 2013 |
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New study cautions use of drugs to block 'niacin flush'
Niacin, or vitamin B3, is the one approved drug that elevates "good" cholesterol (high density lipoprotein, HDL) while depressing "bad" cholesterol (low density lipoprotein , LDL), and has thereby attracted much attention ...
Medical research
Apr 09, 2012 |
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The real culprit behind hardened arteries? Stem cells, says landmark study
One of the top suspects behind killer vascular diseases is the victim of mistaken identity, according to researchers from the University of California, Berkeley, who used genetic tracing to help hunt down ...
Medical research
Jun 06, 2012 |
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Researchers target physiological factors that lead to asthma attack
A new study that identifies ways to reduce the factors that lead to an asthma attack gives hope to asthma sufferers. A UCSF researcher and his colleagues believe they have found a way to help asthma sufferers by impeding ...
Inflammatory disorders
Sep 17, 2012 |
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Long non-coding RNA molecules necessary to regulate differentiation of embryonic stem cells into cardiac cells
When the human genome was sequenced, biologists were surprised to find that very little of the genome—less than 3 percent—corresponds to protein-coding genes. What, they wondered, was all the rest of ...
Medical research
Jan 25, 2013 |
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Tension on gut muscles induces cell invasion in zebrafish intestine, mimicking cancer metastasis
The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering ...
Cancer
Sep 07, 2012 |
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Developing our sense of smell: Biologists pinpoint the origin of olfactory nerve cells
When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone. These sensory neurons are ...
Neuroscience
Mar 25, 2013 |
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Disruption of cellular signaling identified in pulmonary arterial hypertension
(Medical Xpress)—Impairment of a key signaling cascade in the pulmonary blood vessels plays an important role in pulmonary arterial hypertension, a Yale study has found. The study appears in the advance ...
Medical research
Dec 27, 2012 |
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How deficiencies in two genes synergize to halt formation of gut nervous system
Mutations in single genes can cause catastrophic diseases, such as Huntington's Disease or sickle cell anemia. However, many conditions, including cancer, diabetes and birth defects are multigenic, arising ...
Genetics
Jan 31, 2013 |
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Discovery of nitric oxide delivery mechanism may point to new avenue for treating high blood pressure
(Medical Xpress)—Researchers at the University of Virginia School of Medicine have shed new light on blood pressure regulation with the discovery of an unexpected mechanism by which hemoglobin controls the delivery of nitric ...
Medical research
Nov 14, 2012 |
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Stem cells, signaling pathways identified in lung repair
(Medical Xpress) -- Researchers at National Jewish Health have identified cells and signaling molecules that trigger the repair of injured lungs. Stijn De Langhe, PhD, and his colleagues report October 10, 2011, online in ...
Medical research
Oct 11, 2011 |
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Invade and conquer: Nicotine's role in promoting heart and blood vessel disease
Cigarette smoke has long been considered the main risk factor for heart disease. But new research from Brown University in Providence, R.I., shows that nicotine itself, a component of cigarette smoke, can contribute to the ...
Cardiology
Feb 23, 2012 |
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Cell-permeable peptide shows promise for controlling cardiovascular disease
Atherosclerosis – sometimes called "hardening of the arteries" – is a leading cause of death and morbidity in Western countries. A cell-permeable peptide containing the NF-kB nuclear localization sequence (NLS) shows ...
Cardiology
Apr 17, 2013 |
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Research findings breathe new life into lung disease
It turns out the muscle cells on the outside of blood vessels have been wrongly accused for instigating lung disease. New research shows that while these muscle cells are responsible for constricting or dilating the blood ...
Medical research
Oct 24, 2012 |
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Cambridge team first to grow smooth muscle cells from patient skin cells
A Cambridge University research team has for the first time discovered a method of generating different types of vascular smooth muscle cells (SMCs) - the cells which make up the walls of blood vessels - using cells from ...
Cardiology
Jan 26, 2012 |
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