Medical research
Researchers identify potential approach to controlling epileptic seizures
Researchers from Case Western Reserve University have identified a potential new approach to better controlling epileptic seizures.
May 19, 2021
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103
News tagged with sodium channel
Cardiology
Heart cells cozy up to prevent deadly arrhythmias
Blood may seem like a simple fluid, but its chemistry is complex. When too much potassium, for instance, accumulates in the bloodstream, patients may experience deadly irregular heart rhythms.
May 4, 2021
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6
Medical research
Researchers find mechanism underlying muscle weakness in Becker disease
Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibers termed 'plateau potentials' that make them temporarily inactive, says a study published today in eLife.
Apr 27, 2021
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22
Medical research
Investigational new therapy prevents onset of Dravet syndrome symptoms in mice
In a development that may finally offer hope to children with Dravet syndrome and their parents, a promising investigational new therapeutic appears to alter the destructive course of the deadly disease in a mouse model.
Aug 26, 2020
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45
Medical research
Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy
Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a "ball-and-chain" mechanism ...
Mar 18, 2020
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137
Cardiology
Team deciphers how myotonic dystrophy generates lethal heart dysfunctions
Roughly 80% of people with myotonic dystrophy—a common form of muscular dystrophy—experience dangerous heart ailments, and heart rhythm defects are the second-leading cause of death in those with the condition. In a new ...
Feb 27, 2020
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88
Genetics
New therapy stops seizures in mouse model of rare childhood epilepsy
Seizure disorders in babies are frightening and heartbreaking. A new basic science breakthrough offers hope for a potential treatment for rare developmental and epileptic encephalopathies resulting from a single genetic mutation. ...
Feb 20, 2020
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3
Cardiology
Study reveals how low oxygen levels in the heart predispose people to cardiac arrhythmias
Low oxygen levels in the heart have long been known to produce life-threatening arrhythmias, even sudden death. Until now, it was not clear how.
Feb 18, 2020
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299
Cardiology
An atomic view of the trigger for the heartbeat
Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their function, malfunctions, ...
Dec 20, 2019
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269
Cardiology
Can obesity limit antiarrhythmic drug effectiveness?
Atrial fibrillation, also known as AFib, is the most common type of irregular heartbeat, and it is associated with increased mortality. While researchers have identified a causal link between obesity and AFib, the underlying ...
Nov 27, 2019
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