Gene mutations accumulating in cells are typical of the development of cancer. Finnish researchers have found that a similar accumulation of mutations occurs also in some patients with rheumatoid arthritis.
Jun 21, 2017
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(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, ...
Dec 20, 2012
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New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life. Scientists at the Wellcome Sanger Institute, the Cambridge Stem Cell Institute, EMBL's European Bioinformatics ...
Jun 1, 2022
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It's worth noting, in light of recently published research, that a majority of people won't be diagnosed with cancer in their lifetimes. According to the National Cancer Institute, about 40% of people will, which means 60% ...
Dec 13, 2021
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The first comprehensive study of DNA changes in healthy and diseased human bladder tissue has revealed that 'cancer-driving' mutations are common in healthy bladder tissue. The study, conducted by scientists at the Wellcome ...
Oct 1, 2020
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A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build ...
May 4, 2021
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Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but ...
Mar 9, 2021
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In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...
Aug 4, 2022
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Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mutations—may build up at a faster rate. A new study by investigators from Brigham and ...
Apr 20, 2022
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Scientists at the Broad Institute of MIT and Harvard have found that a set of genetic mutations in blood cells that arises during aging may be a major new risk factor for cardiovascular disease. In contrast to inherited genetic ...
Jun 22, 2017
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