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Research reveals possible reason for cholesterol-drug side effects

The U.S. Food and Drug Administration and physicians continue to document that some patients experience fuzzy thinking and memory loss while taking statins, a class of global top-selling cholesterol-lowering ...

Medical research created May 10, 2013 | popularity 4.5 / 5 (11) | comments 13 | with audio podcast

Cholesterol drugs might boost kidney cancer survival

(HealthDay)—Cholesterol-lowering statin drugs that are taken by millions of Americans might also improve survival from a type of kidney cancer called renal cell carcinoma, a new study suggests.

Cancer created May 07, 2013 | popularity 5 / 5 (1) | comments 0

Risk of new-onset diabetes varies with different statins

(HealthDay)—Different types and doses of statins seem to correlate with distinct risks of developing new-onset diabetes mellitus (DM), according to a meta-analysis published in the April 15 issue of The Am ...

Cancer created Apr 11, 2013 | popularity not rated yet | comments 0

Co-Q10 deficiency may relate to concern with statin drugs, higher risk of diabetes

(Medical Xpress)—A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.

Diseases, Conditions, Syndromes created Apr 10, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

High potency statins pose significantly higher risk of kidney injury than low potency, say experts

Patients taking high potency statins for high blood pressure are at a 34% higher risk of being hospitalised for acute kidney injury (AKI), compared with those taking low potency statins, a paper published today in BMJ sugges ...

Cardiology created Mar 19, 2013 | popularity 5 / 5 (1) | comments 1

Cardio risks need evaluation before prescribing statins

(HealthDay)—Physicians may not adequately consider a patient's cardiovascular risk when prescribing statins as preventive therapy, according to a research letter published online March 11 in JAMA Internal Me ...

Cardiology created Mar 15, 2013 | popularity 3 / 5 (1) | comments 0

Study: Mega vitamins won't help after heart attack, chelation treatment might

(HealthDay)—There's mixed news from a much-anticipated clinical trial for people who've suffered a heart attack: While a study found that daily high doses of vitamins and minerals did nothing to improve ...

Cardiology created Mar 11, 2013 | popularity 1 / 5 (1) | comments 0 | with audio podcast

Drug protects against kidney injury from imaging dye in ACS patients

High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0

ACC: Stressful events up incidence of acute MI

(HealthDay)—Stressful events, including hurricanes, earthquakes, and financial crises, correlate with increased incidence of acute myocardial infarction (AMI), according to three studies to be presented ...

Cardiology created Mar 08, 2013 | popularity not rated yet | comments 0

The side effects of statin ads

Television advertising may drive over-diagnosis of high cholesterol and over-treatment with statins, according to a new study by Dr. Jeff Niederdeppe from Cornell University in the US and colleagues. It appears that a trip ...

Cardiology created Mar 07, 2013 | popularity not rated yet | comments 0

Statin use linked to reduced risk of hepatocellular cancer

(HealthDay)—Statin use is associated with a reduced risk of hepatocellular carcinoma (HCC), most strongly in Asian populations, according to a meta-analysis published in the February issue of Gastroenterology.

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0

Merck warns doctors to stop prescribing Tredaptive

Drugmaker Merck says it is suspending its sale of the cholesterol drug Tredaptive and is telling doctors to quit prescribing the medicine.

Medications created Jan 11, 2013 | popularity 1 / 5 (1) | comments 0

Cholesterol medicine affects energy production in muscles

Up to 75 per cent of patients who take statins to treat elevated cholesterol levels may suffer from muscle pain. Scientists at the Center for Healthy Aging at the University of Copenhagen have now identified ...

Cardiology created Jan 03, 2013 | popularity 5 / 5 (2) | comments 0

Open-angle glaucoma up 22 percent in last 10 years

(HealthDay)—The prevalence of open-angle glaucoma has increased more than 20 percent in the last 10 years and currently affects more than 2.7 million Americans age 40 years and older, according to a report ...

Ophthalmology created Jan 01, 2013 | popularity 5 / 5 (1) | comments 0

Statins plus exercise best at lowering cholesterol, study finds

(HealthDay)—People who exercise along with taking statins to lower their high cholesterol levels can dramatically reduce their risk of dying, a large new study suggests.

Cardiology created Nov 28, 2012 | popularity not rated yet | comments 1 | with audio podcast

Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

For more information about Statin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: heart disease , drug , heart attack , cholesterol